This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
CD30L (soluble) (human), (recombinant)
catalog :
ALX-522-028-C010
quantity :
10 µg
citations: 2
Reference
Zheng B, Georgakis G, Li Y, Bharti A, McConkey D, Aggarwal B, et al. Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors. Clin Cancer Res. 2004;10:3207-15 pubmed
Biswas P, Galli A, Capiluppi B, Ciuffreda D, Lazzarin A, Tambussi G. Selective enrichment of CD30-expressing cells within the blast region of lymphocytes from patients with primary HIV infection (PHI). J Biol Regul Homeost Agents. 2002;16:33-6 pubmed
product information
Product ID :
ALX-522-028
Catalog Number :
ALX-522-028-C010
Product Name :
CD30L (soluble) (human), (recombinant)
Product Type :
Protein
Size :
10 µg
list of Pubmed id :
15131062, 12003171
Background :
The CD30 ligand (CD30L, CD153) is a member of the tumor necrosis factor (TNF) family. CD30L is a type II, transmembrane protein expressed on T and B cells, monocytes/macrophages, neutrophils, megakaryocytes, erythroid precursors and eosinophils. After interaction with its receptor CD30, CD30L may induce TNF receptor-associated factor 1 (TRAF1), TRAF2, 3 and 5 recruitment. CD30-CD30L have been reported to be involved in costimulation of T cell proliferation, induction of HIV expression, negative selection and apoptosis as well as in diabetes and several allergic, viral and autoimmune diseases. Historical data has shown that CD30L can be used together with an enhancer (Prod. No. ALX-804-034, see Set Prod. No. ALX-850-066) to detect membrane-bound human CD30. rhsCD30L has also been shown to saturate its receptor at a concentration range of 12-4000ng/ml.
ALTnames :
CD153, TNFSF 8
Specificity :
Binds to human CD30 (Ki-1).
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized. Contains PBS.
Uses :
ELISA: binds to CD30 receptor.
Application Summary :
ELISA
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.