This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
BCMA (human):Fc (human), (recombinant)
catalog :
ALX-522-026-C050
quantity :
50 µg
citations: 10
Reference
Mesin L, Di Niro R, Thompson K, Lundin K, Sollid L. Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro. J Immunol. 2011;187:2867-74 pubmed publisher
Bonci D, Musumeci M, Coppola V, Addario A, Conticello C, Hahne M, et al. Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity. Haematologica. 2008;93:1899-902 pubmed publisher
Bergamin F, Vincent I, Summerfield A, McCullough K. Essential role of antigen-presenting cell-derived BAFF for antibody responses. Eur J Immunol. 2007;37:3122-30 pubmed
Nishio M, Endo T, Tsukada N, Ohata J, Kitada S, Reed J, et al. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. Blood. 2005;106:1012-20 pubmed
Huard B, Arlettaz L, Ambrose C, Kindler V, Mauri D, Roosnek E, et al. BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol. 2004;16:467-75 pubmed
Novak A, Bram R, Kay N, Jelinek D. Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival. Blood. 2002;100:2973-9 pubmed
Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed
Huard B, Schneider P, Mauri D, Tschopp J, French L. T cell costimulation by the TNF ligand BAFF. J Immunol. 2001;167:6225-31 pubmed
Rennert P, Schneider P, Cachero T, Thompson J, Trabach L, Hertig S, et al. A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth. J Exp Med. 2000;192:1677-84 pubmed
Thompson J, Schneider P, Kalled S, Wang L, Lefevre E, Cachero T, et al. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J Exp Med. 2000;192:129-35 pubmed
product information
Product ID :
ALX-522-026
Catalog Number :
ALX-522-026-C050
Product Name :
BCMA (human):Fc (human), (recombinant)
Product Type :
Protein
Size :
50 µg
list of Pubmed id :
21841131, 18838478, 17935087, 15860672, 14978020, 12351410, 11733583, 11714784, 11104810, 10880534
SPECIES REACTIVITY :
Human, Mouse
ALTnames :
TNFRSF 17, B cell maturation protein, CD269
Specificity :
Binds human and mouse BAFF and APRIL.
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized. Contains PBS.
Uses :
ELISA: binds to mouse BAFF). Flow Cytometry: Detection of membrane-bound mouse BAFF and human APRIL in combination with fluorescently labelled Ab to IgG1.
Application Summary :
ELISA, FC
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.