BAFF (soluble) (human), (recombinant) | Enzo Life Sciences ALX-522-025-C010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

BAFF (soluble) (human), (recombinant)

catalog :

ALX-522-025-C010

quantity :

10 µg

citations: 10

Reference
Xu W, Santini P, Matthews A, Chiu A, Plebani A, He B, et al. Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. J Immunol. 2008;181:276-87 pubmed
Chang S, Arendt B, Darce J, Wu X, Jelinek D. A role for BLyS in the activation of innate immune cells. Blood. 2006;108:2687-94 pubmed
Castigli E, Wilson S, Garibyan L, Rachid R, Bonilla F, Schneider L, et al. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat Genet. 2005;37:829-34 pubmed
Novak A, Grote D, Stenson M, Ziesmer S, Witzig T, Habermann T, et al. Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: correlation with disease activity and patient outcome. Blood. 2004;104:2247-53 pubmed
Novak A, Bram R, Kay N, Jelinek D. Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival. Blood. 2002;100:2973-9 pubmed
Rolink A, Tschopp J, Schneider P, Melchers F. BAFF is a survival and maturation factor for mouse B cells. Eur J Immunol. 2002;32:2004-10 pubmed
Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed
Huard B, Schneider P, Mauri D, Tschopp J, French L. T cell costimulation by the TNF ligand BAFF. J Immunol. 2001;167:6225-31 pubmed
Batten M, Groom J, Cachero T, Qian F, Schneider P, Tschopp J, et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med. 2000;192:1453-66 pubmed
Thompson J, Schneider P, Kalled S, Wang L, Lefevre E, Cachero T, et al. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J Exp Med. 2000;192:129-35 pubmed

product information

Product ID :

ALX-522-025

Catalog Number :

ALX-522-025-C010

Product Name :

BAFF (soluble) (human), (recombinant)

Product Type :

Protein

Size :

10 µg

list of Pubmed id :

18566393, 16825497, 16007086, 15251985, 12351410, 12115621, 11733583, 11714784, 11085747, 10880534

SPECIES REACTIVITY :

Human, Mouse

ALTnames :

THANK, zTNF4, TALL-1, BlyS, TNFSF 13B/20, CD257

Specificity :

Binds to human and mouse (weak) BCMA, TACI and BAFF-R.

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Uses :

ELISA: binds to BAFF receptor at 2-100 ng/ml. Detection of receptors of human soluble BAFF on target cells.

Application Summary :

ELISA

Storage :

-20°C