CD40L (soluble) (human), (recombinant) | Enzo Life Sciences ALX-522-015-6010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

CD40L (soluble) (human), (recombinant)

catalog :

ALX-522-015-6010

quantity :

6 x 10 µg

citations: 10

Reference
Jochems C, Tucker J, Vergati M, Boyerinas B, Gulley J, Schlom J, et al. Identification and characterization of agonist epitopes of the MUC1-C oncoprotein. Cancer Immunol Immunother. 2014;63:161-74 pubmed
Hamilton D, Litzinger M, Jales A, Huang B, Fernando R, Hodge J, et al. Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine. Oncotarget. 2013;4:1777-90 pubmed
Ngaotepprutaram T, Kaplan B, Carney S, Crawford R, Kaminski N. Suppression by ?(9)-tetrahydrocannabinol of the primary immunoglobulin M response by human peripheral blood B cells is associated with impaired STAT3 activation. Toxicology. 2013;310:84-91 pubmed publisher
Huang J, Jochems C, Talaie T, Anderson A, Jales A, Tsang K, et al. Elevated serum soluble CD40 ligand in cancer patients may play an immunosuppressive role. Blood. 2012;120:3030-8 pubmed publisher
Dannull J, Schneider T, Lee W, de Rosa N, Tyler D, Pruitt S. Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function. Blood. 2012;119:3113-22 pubmed publisher
Melchers M, Bontjer I, Tong T, Chung N, Klasse P, Eggink D, et al. Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses. J Virol. 2012;86:2488-500 pubmed publisher
Knox P, Davies C, Ioannou M, Eliopoulos A. The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas. J Cell Biol. 2011;192:391-9 pubmed publisher
Vardouli L, Lindqvist C, Vlahou K, Loskog A, Eliopoulos A. Adenovirus delivery of human CD40 ligand gene confers direct therapeutic effects on carcinomas. Cancer Gene Ther. 2009;16:848-60 pubmed publisher
Williams K, Young S, Negus A, Young L, Adams D, Afford S. C4b binding protein binds to CD154 preventing CD40 mediated cholangiocyte apoptosis: a novel link between complement and epithelial cell survival. PLoS ONE. 2007;2:e159 pubmed
Zheng B, Georgakis G, Li Y, Bharti A, McConkey D, Aggarwal B, et al. Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors. Clin Cancer Res. 2004;10:3207-15 pubmed

product information

Product ID :

ALX-522-015

Catalog Number :

ALX-522-015-6010

Product Name :

CD40L (soluble) (human), (recombinant)

Product Type :

Protein

Size :

6 x 10 µg

list of Pubmed id :

24233342, 24125763, 23727458, 22932804, 22323449, 22205734, 21282461, 19461675, 17225862, 15131062

ALTnames :

CD154, TNFSF 5, gp39

Specificity :

Binds to human CD40.

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Uses :

ELISA: binds to CD40 receptor at 1-10 ng/ml.

Application Summary :

ELISA

Storage :

-20°C