TNF-α (soluble) (mouse), (recombinant) | Enzo Life Sciences ALX-522-009-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

TNF-α (soluble) (mouse), (recombinant)

catalog :

ALX-522-009-C050

quantity :

50 µg

citations: 3

Reference
Geering B, Gurzeler U, Federzoni E, Kaufmann T, Simon H. A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood. 2011;117:5953-62 pubmed publisher
Burns K, Janssens S, Brissoni B, Olivos N, Beyaert R, Tschopp J. Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med. 2003;197:263-8 pubmed
Schneider P, Holler N, Bodmer J, Hahne M, Frei K, Fontana A, et al. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med. 1998;187:1205-13 pubmed

product information

Product ID :

ALX-522-009

Catalog Number :

ALX-522-009-C050

Product Name :

TNF-α (soluble) (mouse), (recombinant)

Product Type :

Protein

Size :

50 µg

list of Pubmed id :

21478427, 12538665, 9547332

SPECIES REACTIVITY :

Human, Mouse, Rat

ALTnames :

Tumor necrosis factor-α, TNFSF 2

Specificity :

Binds to human, mouse and rat TNF-R1 and less efficiently to TNF-R2. In the presence of cross-linking enhancer (see Set Prod. No. ALX-850-061), TNF-α shows a significantly higher affinity for TNF-R2 than for TNF-R1, mimicking the characteristics of membrane-bound TNF-α.

Purity :

≥90% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Uses :

ELISA: binds to human TNF-R1 receptor.

Application Summary :

ELISA

Storage :

-20°C