TRAIL-R2 (human):Fc (human), (recombinant) (FITC conjugate) | Enzo Life Sciences ALX-522-005F-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

TRAIL-R2 (human):Fc (human), (recombinant) (FITC conjugate)

catalog :

ALX-522-005F-C050

quantity :

50 µg

citations: 9

Reference
Holler N, Tardivel A, Kovacsovics Bankowski M, Hertig S, Gaide O, Martinon F, et al. Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol. 2003;23:1428-40 pubmed
Schmaltz C, Alpdogan O, Kappel B, Muriglan S, Rotolo J, Ongchin J, et al. T cells require TRAIL for optimal graft-versus-tumor activity. Nat Med. 2002;8:1433-7 pubmed
Ursini Siegel J, Zhang W, Altmeyer A, Hatada E, Do R, Yagita H, et al. TRAIL/Apo-2 ligand induces primary plasma cell apoptosis. J Immunol. 2002;169:5505-13 pubmed
Söderström T, Poukkula M, Holmström T, Heiskanen K, Eriksson J. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8. J Immunol. 2002;169:2851-60 pubmed
Lunemann J, Waiczies S, Ehrlich S, Wendling U, Seeger B, Kamradt T, et al. Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells. J Immunol. 2002;168:4881-8 pubmed
Lu G, Janjic B, Janjic J, Whiteside T, Storkus W, Vujanovic N. Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand. J Immunol. 2002;168:1831-9 pubmed
Dorr J, Waiczies S, Wendling U, Seeger B, Zipp F. Induction of TRAIL-mediated glioma cell death by human T cells. J Neuroimmunol. 2002;122:117-24 pubmed
Muhlenbeck F, Schneider P, Bodmer J, Schwenzer R, Hauser A, Schubert G, et al. The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation. J Biol Chem. 2000;275:32208-13 pubmed
Holler N, Kataoka T, Bodmer J, Romero P, Romero J, Deperthes D, et al. Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors. J Immunol Methods. 2000;237:159-73 pubmed

product information

Product ID :

ALX-522-005F

Catalog Number :

ALX-522-005F-C050

Product Name :

TRAIL-R2 (human):Fc (human), (recombinant) (FITC conjugate)

Conjugation :

FITC

Product Type :

Protein

Size :

50 µg

list of Pubmed id :

12556501, 12426560, 12421926, 12218097, 11994437, 11823516, 11777550, 10807904, 10725460

SPECIES REACTIVITY :

Human, Mouse

ALTnames :

DR5, TNFRSF 10B, KILLER, CD262

Specificity :

Binds human and mouse TRAIL.

Purity :

≥95% (SDS-PAGE)

Buffer :

Liquid. In PBS containing 0.02% sodium azide.

Uses :

Flow Cytometry: detection of TRAIL cell surface expression.

Application Summary :

Storage :

-20°C