TRAIL-R2 (human):Fc (human), (recombinant) | Enzo Life Sciences ALX-522-005-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

TRAIL-R2 (human):Fc (human), (recombinant)

catalog :

ALX-522-005-C050

quantity :

50 µg

citations: 10

Reference
Li Z, Zhao J, Tikhanovich I, Kuravi S, Helzberg J, Dorko K, et al. Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression. Cell Death Differ. 2016;23:583-95 pubmed publisher
Cazanave S, Mott J, Bronk S, Werneburg N, Fingas C, Meng X, et al. Death receptor 5 signaling promotes hepatocyte lipoapoptosis. J Biol Chem. 2011;286:39336-48 pubmed publisher
Laussmann M, Passante E, Dussmann H, Rauen J, Würstle M, Delgado M, et al. Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8. Cell Death Differ. 2011;18:1584-97 pubmed publisher
Holler N, Tardivel A, Kovacsovics Bankowski M, Hertig S, Gaide O, Martinon F, et al. Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol. 2003;23:1428-40 pubmed
Schmaltz C, Alpdogan O, Kappel B, Muriglan S, Rotolo J, Ongchin J, et al. T cells require TRAIL for optimal graft-versus-tumor activity. Nat Med. 2002;8:1433-7 pubmed
Ursini Siegel J, Zhang W, Altmeyer A, Hatada E, Do R, Yagita H, et al. TRAIL/Apo-2 ligand induces primary plasma cell apoptosis. J Immunol. 2002;169:5505-13 pubmed
Söderström T, Poukkula M, Holmström T, Heiskanen K, Eriksson J. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8. J Immunol. 2002;169:2851-60 pubmed
Lunemann J, Waiczies S, Ehrlich S, Wendling U, Seeger B, Kamradt T, et al. Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells. J Immunol. 2002;168:4881-8 pubmed
Lu G, Janjic B, Janjic J, Whiteside T, Storkus W, Vujanovic N. Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand. J Immunol. 2002;168:1831-9 pubmed
Dorr J, Waiczies S, Wendling U, Seeger B, Zipp F. Induction of TRAIL-mediated glioma cell death by human T cells. J Neuroimmunol. 2002;122:117-24 pubmed

product information

Product ID :

ALX-522-005

Catalog Number :

ALX-522-005-C050

Product Name :

TRAIL-R2 (human):Fc (human), (recombinant)

Product Type :

Protein

Size :

50 µg

list of Pubmed id :

26470730, 21941003, 21455219, 12556501, 12426560, 12421926, 12218097, 11994437, 11823516, 11777550

SPECIES REACTIVITY :

Human, Mouse

ALTnames :

DR5, TNFRSF 10B, KILLER, CD262

Specificity :

Binds human and mouse TRAIL.

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Uses :

ELISA: binds to TRAIL at 10-100 ng/ml.

Application Summary :

ELISA

Storage :

-20°C