Fas (human):Fc (human), (recombinant) | Enzo Life Sciences ALX-522-002-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Fas (human):Fc (human), (recombinant)

catalog :

ALX-522-002-C050

quantity :

50 µg

citations: 10

Reference
Laussmann M, Passante E, Dussmann H, Rauen J, Würstle M, Delgado M, et al. Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8. Cell Death Differ. 2011;18:1584-97 pubmed publisher
Hou W, Kang H, Kim B. Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J Exp Med. 2009;206:313-28 pubmed publisher
Roessner K, Wolfe J, Shi C, Sigal L, Huber S, Budd R. High expression of Fas ligand by synovial fluid-derived gamma delta T cells in Lyme arthritis. J Immunol. 2003;170:2702-10 pubmed
Holler N, Tardivel A, Kovacsovics Bankowski M, Hertig S, Gaide O, Martinon F, et al. Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol. 2003;23:1428-40 pubmed
Huard B, Schneider P, Mauri D, Tschopp J, French L. T cell costimulation by the TNF ligand BAFF. J Immunol. 2001;167:6225-31 pubmed
Petit F, Arnoult D, Lelievre J, Moutouh de Parseval L, Hance A, Schneider P, et al. Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death. J Biol Chem. 2002;277:1477-87 pubmed
Schlapbach R, Spanaus K, Malipiero U, Lens S, Tasinato A, Tschopp J, et al. TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia. Eur J Immunol. 2000;30:3680-8 pubmed
Ciesielski Treska J, Ulrich G, Chasserot Golaz S, Zwiller J, Revel M, Aunis D, et al. Mechanisms underlying neuronal death induced by chromogranin A-activated microglia. J Biol Chem. 2001;276:13113-20 pubmed
Bodmer J, Meier P, Tschopp J, Schneider P. Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL. J Biol Chem. 2000;275:20632-7 pubmed
Holler N, Kataoka T, Bodmer J, Romero P, Romero J, Deperthes D, et al. Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors. J Immunol Methods. 2000;237:159-73 pubmed

product information

Product ID :

ALX-522-002

Catalog Number :

ALX-522-002-C050

Product Name :

Fas (human):Fc (human), (recombinant)

Product Type :

Protein

Size :

50 µg

list of Pubmed id :

21455219, 19204109, 12594300, 12556501, 11714784, 11689551, 11169411, 11124958, 10748154, 10725460

SPECIES REACTIVITY :

Human, Mouse, Rat

ALTnames :

CD95, APO-1, TNFRSF 6

Specificity :

Binds human, mouse and rat FasL (APO-1L; CD95L; CD178).

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Uses :

ELISA: binds to FasL at 10-100 ng/ml.

Application Summary :

ELISA

Storage :

-20°C