8-Hydroxyguanine | Enzo Life Sciences ALX-480-091-M010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

8-Hydroxyguanine

catalog :

ALX-480-091-M010

quantity :

10 mg

citations: 8

Reference
Hyun J, Choi J, Zeng H, Lee Y, Kim H, Yoon S, et al. Leukemic cell line, KG-1 has a functional loss of hOGG1 enzyme due to a point mutation and 8-hydroxydeoxyguanosine can kill KG-1. Oncogene. 2000;19:4476-9 pubmed
Tretyakova N, Wishnok J, Tannenbaum S. Peroxynitrite-induced secondary oxidative lesions at guanine nucleobases: chemical stability and recognition by the Fpg DNA repair enzyme. Chem Res Toxicol. 2000;13:658-64 pubmed
Helbock H, Beckman K, Ames B. 8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage. Methods Enzymol. 1999;300:156-66 pubmed
Everett S, Patel K, Dennis M, Smith K, Stratford M, Wardman P. Oxidative denitrification of the antitumour drug hydroxyguanidine. Free Radic Biol Med. 1998;24:1-10 pubmed
Jaruga P, Zastawny T, Skokowski J, Dizdaroglu M, Olinski R. Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer. FEBS Lett. 1994;341:59-64 pubmed
Shigenaga M, Aboujaoude E, Chen Q, Ames B. Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection. Methods Enzymol. 1994;234:16-33 pubmed
Zastawny T, Altman S, Randers Eichhorn L, Madurawe R, Lumpkin J, Dizdaroglu M, et al. DNA base modifications and membrane damage in cultured mammalian cells treated with iron ions. Free Radic Biol Med. 1995;18:1013-22 pubmed
Spencer J, Jenner A, Chimel K, Aruoma O, Cross C, Wu R, et al. DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells. FEBS Lett. 1995;374:233-6 pubmed

product information

Product ID :

ALX-480-091

Catalog Number :

ALX-480-091-M010

Product Name :

8-Hydroxyguanine

Product Type :

Biochemical

Size :

10 mg

list of Pubmed id :

11002420, 10898599, 9919519, 9436608, 8137923, 7808289, 7628727, 7589542

Product Description :

Oxidative DNA degradation product.

ALTnames :

8-Oxoguanine, 7,8-Dihydro-8-oxoguanine, 8-oxoG

Purity :

≥90% (HPLC (UV))

Storage :

-20°C