This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
8-Hydroxy-2'-deoxyguanosine
catalog :
ALX-480-090-M001
quantity :
1 mg
citations: 7
Reference
Cappelli E, Degan P, Thompson L, Frosina G. Efficient repair of 8-oxo-7,8-dihydrodeoxyguanosine in human and hamster xeroderma pigmentosum D cells. Biochemistry. 2000;39:10408-12 pubmed
Cooke M, Evans M, Herbert K, Lunec J. Urinary 8-oxo-2'-deoxyguanosine--source, significance and supplements. Free Radic Res. 2000;32:381-97 pubmed
Asagoshi K, Yamada T, Terato H, Ohyama Y, Monden Y, Arai T, et al. Distinct repair activities of human 7,8-dihydro-8-oxoguanine DNA glycosylase and formamidopyrimidine DNA glycosylase for formamidopyrimidine and 7,8-dihydro-8-oxoguanine. J Biol Chem. 2000;275:4956-64 pubmed
Markesbery W, Carney J. Oxidative alterations in Alzheimer's disease. Brain Pathol. 1999;9:133-46 pubmed
Shigenaga M, Aboujaoude E, Chen Q, Ames B. Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection. Methods Enzymol. 1994;234:16-33 pubmed
Lin T, Cheng J, Ishiguro K, Sartorelli A. 8-Substituted guanosine and 2'-deoxyguanosine derivatives as potential inducers of the differentiation of Friend erythroleukemia cells. J Med Chem. 1985;28:1194-8 pubmed
Park E, Shigenaga M, Degan P, Korn T, Kitzler J, Wehr C, et al. Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column. Proc Natl Acad Sci U S A. 1992;89:3375-9 pubmed
product information
Product ID :
ALX-480-090
Catalog Number :
ALX-480-090-M001
Product Name :
8-Hydroxy-2'-deoxyguanosine
Product Type :
Biochemical
Size :
1 mg
list of Pubmed id :
10956030, 10766407, 10671534, 9989456, 7808289, 3861870, 1565629
Product Description :
Oxidative DNA degradation product.
ALTnames :
8-OHdG
Purity :
≥98%
Storage :
Ambient
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.