8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate . sodium salt | Enzo Life Sciences ALX-480-088-M001 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate . sodium salt

catalog :

ALX-480-088-M001

quantity :

1 mg

citations: 2

Reference
Butt E, Nolte C, Schulz S, Beltman J, Beavo J, Jastorff B, et al. Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-para-chlorophenylthio-cGMP. Biochem Pharmacol. 1992;43:2591-600 pubmed
Geiger J, Nolte C, Butt E, Sage S, Walter U. Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets. Proc Natl Acad Sci U S A. 1992;89:1031-5 pubmed

product information

Product ID :

ALX-480-088

Catalog Number :

ALX-480-088-M001

Product Name :

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate . sodium salt

Product Type :

Biochemical

Size :

1 mg

list of Pubmed id :

1321624, 1310537

Product Description :

Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels. Higher activation potential as compared to cGMP; excellent cell membrane permeability and phosphodiesterase stability. Preferred alternative to unsuitable analogs such as dibutyryl-cGMP.

ALTnames :

8-pCPT-cGMP . Na

Purity :

≥99% (HPLC)

Storage :

-20°C