8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer . triethylammonium salt (high purity) | Enzo Life Sciences ALX-480-032-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer . triethylammonium salt (high purity)

catalog :

ALX-480-032-C100

quantity :

100 µg

citations: 4

Reference
Chen S, Osaki N, Shimotoyodome A. Green tea catechins enhance norepinephrine-induced lipolysis via a protein kinase A-dependent pathway in adipocytes. Biochem Biophys Res Commun. 2015;461:1-7 pubmed publisher
Kramer R, Tibbs G. Antagonists of cyclic nucleotide-gated channels and molecular mapping of their site of action. J Neurosci. 1996;16:1285-93 pubmed
Butt E, Eigenthaler M, Genieser H. (Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. Eur J Pharmacol. 1994;269:265-8 pubmed
Gamm D, Francis S, Angelotti T, Corbin J, Uhler M. The type II isoform of cGMP-dependent protein kinase is dimeric and possesses regulatory and catalytic properties distinct from the type I isoforms. J Biol Chem. 1995;270:27380-8 pubmed

product information

Product ID :

ALX-480-032

Catalog Number :

ALX-480-032-C100

Product Name :

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer . triethylammonium salt (high purity)

Product Type :

Biochemical

Size :

100 µg

list of Pubmed id :

25849890, 8778280, 7851503, 7593002

Product Description :

Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS (Prod. No. ALX-480-072) or Rp-8-Br-cGMPS (Prod. No. BML-CN216).

ALTnames :

Rp-8-pCPT-cGMPS . TEA, 8-pCPT-cGMPS . TEA, Rp-Isomer

Purity :

≥99% (HPLC)

Storage :

-20°C