Nonactin | Enzo Life Sciences ALX-450-008-M005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Nonactin

catalog :

ALX-450-008-M005

quantity :

5 mg

citations: 7

Reference
Karakuş E, Pekyardimci S, Kiliç E. A new potentiometric ammonium electrode for biosensor construction. Artif Cells Blood Substit Immobil Biotechnol. 2006;34:523-34 pubmed
Meyers E, Pansy F, Perlman D, Smith D, WEISENBORN F. THE IN VITRO ACTIVITY OF NONACTIN AND ITS HOMOLOGS: MONACTIN, DINACTIN AND TRINACTIN. J Antibiot (Tokyo). 1965;18:128-9 pubmed
Garcia C, Júnior L, Neto G. Determination of potassium ions in pharmaceutical samples by FIA using a potentiometric electrode based on ionophore nonactin occluded in EVA membrane. J Pharm Biomed Anal. 2003;31:11-8 pubmed
Borrel M, Pereira E, Fiallo M, Garnier Suillerot A. Mobile ionophores are a novel class of P-glycoprotein inhibitors. The effects of ionophores on 4'-O-tetrahydropyranyl-adriamycin incorporation in K562 drug-resistant cells. Eur J Biochem. 1994;223:125-33 pubmed
Graven S, Lardy H, Rutter A. Antibiotics as tools for metabolic studies. VI. Damped oscillatory swelling of mitochondria induced by nonactin, monactin, dinactin, and trinactin. Biochemistry. 1966;5:1735-42 pubmed
Kohler W, Thrum H, Schlegel R. [Antibacterial spectrum of nonactin with special consideration of Corynebacteriaceae]. Zentralbl Bakteriol Orig. 1964;194:457-61 pubmed
Graven S, Lardy H, Johnson D, Rutter A. Antibiotics as tools for metabolic studies. V. Effect of nonactin, monactin, dinactin, and trinactin on oxidative phosphorylation and adenosine triphosphatase induction. Biochemistry. 1966;5:1729-35 pubmed

product information

Product ID :

ALX-450-008

Catalog Number :

ALX-450-008-M005

Product Name :

Nonactin

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

16893815, 14336167, 12560044, 7518390, 5962273, 4953484, 4225380

Product Description :

Macrotetrolide antibiotic. Monovalent cation ionophore with high selectivity for ammonium and potassium. Specifically inhibits the processing of cytoplasmic precursor proteins destined for the mitochondria. Inhibits the effects on P170 glycoprotein-mediated efflux of chemotherapeutic agents in multidrug resistant (MDR) cancer cells.

ALTnames :

Polynactin, Werramycin A

Purity :

≥98% (TLC) (Total homologs)

Storage :

-20°C