This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Teniposide
catalog :
ALX-400-053-M100
quantity :
100 mg
citations: 5
Reference
Liu M, Chen Y, Zhang L, Wang Q, Ma X, Li X, et al. Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II. J Biol Chem. 2015;290:14418-29 pubmed publisher
Li J, Chen W, Zhang P, Li N. Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma. World J Surg Oncol. 2006;4:41 pubmed
de Jong S, Kooistra A, de Vries E, Mulder N, Zijlstra J. Topoisomerase II as a target of VM-26 and 4'-(9-acridinylamino)methanesulfon-m-aniside in atypical multidrug resistant human small cell lung carcinoma cells. Cancer Res. 1993;53:1064-71 pubmed
Ross W, Rowe T, Glisson B, Yalowich J, Liu L. Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage. Cancer Res. 1984;44:5857-60 pubmed
Relling M, Evans R, Dass C, Desiderio D, Nemec J. Human cytochrome P450 metabolism of teniposide and etoposide. J Pharmacol Exp Ther. 1992;261:491-6 pubmed
product information
Product ID :
ALX-400-053
Catalog Number :
ALX-400-053-M100
Product Name :
Teniposide
Product Type :
Biochemical
Size :
100 mg
list of Pubmed id :
25914138, 16822322, 8382551, 6094001, 1578365
Product Description :
Glycoside-derivative of podophyllotoxin. Has cytostatic effect. Inhibits topoisomerase II. Induces apoptosis.
ALTnames :
(5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]furo[3’,4’:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 4’-Demethylepipodophyllotoxin-β-D-thenylidine glucoside
Purity :
≥97% (HPLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.