Busulfan | Enzo Life Sciences ALX-400-048-G010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Busulfan

catalog :

ALX-400-048-G010

quantity :

10 g

citations: 3

Reference
Probin V, Wang Y, Zhou D. Busulfan-induced senescence is dependent on ROS production upstream of the MAPK pathway. Free Radic Biol Med. 2007;42:1858-65 pubmed
Morales Ramírez P, Miranda Pasaye S, Cruz Vallejo V, Vallarino Kelly T, Mendiola Cruz M. Kinetic of genotoxic expression in the pharmacodynamics of busulfan. Arch Med Res. 2006;37:316-21 pubmed
Iwamoto T, Hiraku Y, Oikawa S, Mizutani H, Kojima M, Kawanishi S. DNA intrastrand cross-link at the 5'-GA-3' sequence formed by busulfan and its role in the cytotoxic effect. Cancer Sci. 2004;95:454-8 pubmed

product information

Product ID :

ALX-400-048

Catalog Number :

ALX-400-048-G010

Product Name :

Busulfan

Product Type :

Biochemical

Size :

10 g

list of Pubmed id :

17512465, 16513478, 15132775

Product Description :

Antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5’-GA-3’ and, to a lesser extent, at 5’-GG-3’ sequences. Forms an intrastrand cross-link at the 5’-GA-3’ sequence, in addition to monoalkylation. Selectively induces normal human fibroblast senescence through Erk and p38 pathways.

ALTnames :

1,4-Butanediol dimethanesulfonate

Purity :

≥98% (Assay)

Storage :

-20°C