This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Sodium orthovanadate
catalog :
ALX-400-032-G005
quantity :
5 g
citations: 4
Reference
Swarup G, Cohen S, Garbers D. Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate. Biochem Biophys Res Commun. 1982;107:1104-9 pubmed
Föhr K, Scott J, Ahnert Hilger G, Gratzl M. Characterization of the inositol 1,4,5-trisphosphate-induced calcium release from permeabilized endocrine cells and its inhibition by decavanadate and p-hydroxymercuribenzoate. Biochem J. 1989;262:83-9 pubmed
Strupish J, Wojcikiewicz R, Challiss R, Safrany S, Willcocks A, Potter B, et al. Is decavanadate a specific inositol 1,4,5-trisphosphate receptor antagonist?. Biochem J. 1991;277 ( Pt 1):294 pubmed
Seargeant L, Stinson R. Inhibition of human alkaline phosphatases by vanadate. Biochem J. 1979;181:247-50 pubmed
product information
Product ID :
ALX-400-032
Catalog Number :
ALX-400-032-G005
Product Name :
Sodium orthovanadate
Product Type :
Biochemical
Size :
5 g
list of Pubmed id :
6291515, 2818578, 1649602, 486156
Product Description :
Potent inhibitor of alkaline phosphatase and tyrosine phosphates. Regarding decavanadate: across the pH range of 1-13, simple aqueous solutions of [VO4]3- ion involve a dozen or more ionic species, both monomeric and oligomeric, whose abundances depend strongly on pH and [VO4]3- concentration. At pH 3.75 a stable complex can be prepared (see below in Fohr et al.) which contains ten vanadium atoms and hence is a decavanadate ion. When diluted to pH 7.2, the decavanadate species has a half-life time of about 2 hours. Fohr et al., also provide directions for generating control solutions of mixed vanadate complexes in which decavanadate is absent and monomeric orthovanadate is present. Decavanadate inhibits inositol 1,4,5-trisphosphate- (IP3) induced calcium release from permeabilized endocrine cells and the binding of [3H]IP3 to its receptor in cerebellar and adrenal cortical membranes.
ALTnames :
Sodium vanadate
Purity :
≥90% (dry basis titration)
Storage :
Ambient
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.