This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Thimerosal
catalog :
ALX-400-013-G005
quantity :
5 g
citations: 8
Reference
Madi A. Being on the track of thimerosal. Review. Acta Microbiol Immunol Hung. 2005;52:95-103 pubmed
Bultynck G, Szlufcik K, Kasri N, Assefa Z, Callewaert G, Missiaen L, et al. Thimerosal stimulates Ca2+ flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction. Biochem J. 2004;381:87-96 pubmed
Baskin D, Ngo H, Didenko V. Thimerosal induces DNA breaks, caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts. Toxicol Sci. 2003;74:361-8 pubmed
Elferink J. Thimerosal: a versatile sulfhydryl reagent, calcium mobilizer, and cell function-modulating agent. Gen Pharmacol. 1999;33:1-6 pubmed
Sayers L, Brown G, Michell R, Michelangeli F. The effects of thimerosal on calcium uptake and inositol 1,4,5-trisphosphate-induced calcium release in cerebellar microsomes. Biochem J. 1993;289 ( Pt 3):883-7 pubmed
Zaidi N, Lagenaur C, Hilkert R, Xiong H, Abramson J, Salama G. Disulfide linkage of biotin identifies a 106-kDa Ca2+ release channel in sarcoplasmic reticulum. J Biol Chem. 1989;264:21737-47 pubmed
Swann K. Thimerosal causes calcium oscillations and sensitizes calcium-induced calcium release in unfertilized hamster eggs. FEBS Lett. 1991;278:175-8 pubmed
Miyazaki S, Shirakawa H, Nakada K, Honda Y, Yuzaki M, Nakade S, et al. Antibody to the inositol trisphosphate receptor blocks thimerosal-enhanced Ca(2+)-induced Ca2+ release and Ca2+ oscillations in hamster eggs. FEBS Lett. 1992;309:180-4 pubmed
product information
Product ID :
ALX-400-013
Catalog Number :
ALX-400-013-G005
Product Name :
Thimerosal
Product Type :
Biochemical
Size :
5 g
list of Pubmed id :
15957237, 15015936, 12773768, 10428009, 8435083, 2480955, 1991508, 1324195
Product Description :
Modulates thiol groups in biological systems, especially in those involving cAMP, Ca2+ and inositol phosphate. Causes a release of calcium from intracellular stores in many cells types. Has toxic effects on several cell types. Induces apoptosis in vitro.
ALTnames :
Ethyl mercurithiosalicylic acid . Na, Mercurothiolate
Purity :
≥98% (Assay)
Storage :
Ambient
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.