Diosmin | Enzo Life Sciences ALX-385-031-G025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Diosmin

catalog :

ALX-385-031-G025

quantity :

25 g

citations: 10

Reference
Martínez Conesa C, Vicente Ortega V, Yáñez Gascón M, Alcaraz Baños M, Canteras Jordana M, Benavente García O, et al. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. J Agric Food Chem. 2005;53:6791-7 pubmed
Pehlivan M, Hazinedaroglu S, Kayaoglu H, Erkek A, Keklik T, Canbolat O, et al. The effect of diosmin hesperidin on intestinal ischaemia--reperfusion injury. Acta Chir Belg. 2004;104:715-8 pubmed
Zheng Q, Hirose Y, Yoshimi N, Murakami A, Koshimizu K, Ohigashi H, et al. Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells. J Cancer Res Clin Oncol. 2002;128:539-46 pubmed
Crespo M, Galvez J, Cruz T, Ocete M, Zarzuelo A. Anti-inflammatory activity of diosmin and hesperidin in rat colitis induced by TNBS. Planta Med. 1999;65:651-3 pubmed
Melzig M, Loose R. Inhibition of lipopolysaccharide (LPS)-induced endothelial cytotoxicity by diosmin. Pharmazie. 1999;54:298-9 pubmed
Teel R, Huynh H. Modulation by phytochemicals of cytochrome P450-linked enzyme activity. Cancer Lett. 1998;133:135-41 pubmed
Ciolino H, Wang T, Yeh G. Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity. Cancer Res. 1998;58:2754-60 pubmed
Yang M, Tanaka T, Hirose Y, Deguchi T, Mori H, Kawada Y. Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice. Int J Cancer. 1997;73:719-24 pubmed
Ibegbuna V, Nicolaides A, Sowade O, Leon M, Geroulakos G. Venous elasticity after treatment with Daflon 500 mg. Angiology. 1997;48:45-9 pubmed
Cypriani B, Limasset B, Carrie M, Le Doucen C, Roussie M, de Paulet A, et al. Antioxidant activity of micronized diosmin on oxygen species from stimulated human neutrophils. Biochem Pharmacol. 1993;45:1531-5 pubmed

product information

Product ID :

ALX-385-031

Catalog Number :

ALX-385-031-G025

Product Name :

Diosmin

Product Type :

Biochemical

Size :

25 g

list of Pubmed id :

16104801, 15663281, 12384797, 10575379, 10234742, 10072162, 9661887, 9398052, 8995343, 8385947

Product Description :

Flavonoid glycoside. Reduces venous hyperpressure. Reduces capillary hyperpermeability and the expression of endothelial adhesion molecules (ICAM1, VCAM1). Effectively inhibits the P-glycoprotein (Pgp)-mediated efflux in cells. Anti-inflammatory.

ALTnames :

3’,5,7-Trihydroxy-4’-methoxyflavone 7-rutinoside

Purity :

≥90% (HPLC)

Storage :

+4°C