This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Myricetin
catalog :
ALX-385-012-M050
quantity :
50 mg
citations: 9
Reference
Lee K, Kang N, Rogozin E, Kim H, Cho Y, Bode A, et al. Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis. 2007;28:1918-27 pubmed
Holder S, Zemskova M, Zhang C, Tabrizizad M, Bremer R, Neidigh J, et al. Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. Mol Cancer Ther. 2007;6:163-72 pubmed
Lu J, Papp L, Fang J, Rodriguez Nieto S, Zhivotovsky B, Holmgren A. Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity. Cancer Res. 2006;66:4410-8 pubmed
Ko C, Shen S, Hsu C, Chen Y. Mitochondrial-dependent, reactive oxygen species-independent apoptosis by myricetin: roles of protein kinase C, cytochrome c, and caspase cascade. Biochem Pharmacol. 2005;69:913-27 pubmed
Ko C, Shen S, Lee T, Chen Y. Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells. Mol Cancer Ther. 2005;4:281-90 pubmed
Babich H, Zuckerbraun H. In vitro cytotoxicity of glyco-S-nitrosothiols. a novel class of nitric oxide donors. Toxicol In Vitro. 2001;15:181-90 pubmed
Tsai S, Liang Y, Lin Shiau S, Lin J. Suppression of TNFalpha-mediated NFkappaB activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells. J Cell Biochem. 1999;74:606-15 pubmed
Ong K, Khoo H. Biological effects of myricetin. Gen Pharmacol. 1997;29:121-6 pubmed
Rice Evans C, Miller N, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med. 1996;20:933-56 pubmed
product information
Product ID :
ALX-385-012
Catalog Number :
ALX-385-012-M050
Product Name :
Myricetin
Product Type :
Biochemical
Size :
50 mg
list of Pubmed id :
17693661, 17218638, 16618767, 15748703, 15713899, 11377090, 10440930, 9251891, 8743980
Product Description :
Antioxidant flavonoid. Has antitumor and chemopreventive properties. Anti-inflammatory. Inhibits NF-κB activation. PIM1 kinase inhibitor IC50=0.78µM.
ALTnames :
3,3',4',5,5',7-Hexahydroxyflavone
Purity :
≥90% (HPLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.