Hygromycin B (sterile-filtered solution in PBS) | Enzo Life Sciences ALX-380-306-G001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Hygromycin B (sterile-filtered solution in PBS)

catalog :

ALX-380-306-G001

quantity :

1 g

citations: 7

Reference
Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed publisher
Stolz A, Putyrski M, Kutle I, Huber J, Wang C, Major V, et al. Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins. EMBO J. 2017;36:549-564 pubmed publisher
McGaha S, Champney W. Hygromycin B inhibition of protein synthesis and ribosome biogenesis in Escherichia coli. Antimicrob Agents Chemother. 2007;51:591-6 pubmed
Ganoza M, Kiel M. A ribosomal ATPase is a target for hygromycin B inhibition on Escherichia coli ribosomes. Antimicrob Agents Chemother. 2001;45:2813-9 pubmed
Brodersen D, Clemons W, Carter A, Morgan Warren R, Wimberly B, Ramakrishnan V. The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell. 2000;103:1143-54 pubmed
Chen G, Branton P, Shore G. Induction of p53-independent apoptosis by hygromycin B: suppression by Bcl-2 and adenovirus E1B 19-kDa protein. Exp Cell Res. 1995;221:55-9 pubmed
Lacal J, Carrasco L. Antiviral effects of hygromycin B, a translation inhibitor nonpermeant to uninfected cells. Antimicrob Agents Chemother. 1983;24:273-5 pubmed

product information

Product ID :

ALX-380-306

Catalog Number :

ALX-380-306-G001

Product Name :

Hygromycin B (sterile-filtered solution in PBS)

Product Type :

Biochemical

Size :

1 g

list of Pubmed id :

17043113, 11557474, 11163189, 7589255, 6314888

Product Description :

Antibiotic. Inhibits growth of prokaryotic and eukaryotic microorganisms and mammalian cells. Inhibits protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA. Penetrates cells that have been permeabilized by virus infection, hence it can act as an effective antiviral agent.

ALTnames :

O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-O-β-D-talopyranosyl(1-5)-2-deoxy-N3-methyl-D-streptamine

Purity :

≥90% (HPLC)

Storage :

+4°C