Ofloxacin | Enzo Life Sciences ALX-380-297-G005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Ofloxacin

catalog :

ALX-380-297-G005

quantity :

5 g

citations: 10

Reference
Shandil R, Jayaram R, Kaur P, Gaonkar S, Suresh B, Mahesh B, et al. Moxifloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis: evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy. Antimicrob Agents Chemother. 2007;51:576-82 pubmed
Shi R, Zhang J, Li C, Kazumi Y, Sugawara I. Emergence of ofloxacin resistance in Mycobacterium tuberculosis clinical isolates from China as determined by gyrA mutation analysis using denaturing high-pressure liquid chromatography and DNA sequencing. J Clin Microbiol. 2006;44:4566-8 pubmed
Fernández Tornero C, Garcia E, de Pascual Teresa B, López R, Gimenez Gallego G, Romero A. Ofloxacin-like antibiotics inhibit pneumococcal cell wall-degrading virulence factors. J Biol Chem. 2005;280:19948-57 pubmed
Drlica K. Mechanism of fluoroquinolone action. Curr Opin Microbiol. 1999;2:504-8 pubmed
Morrissey I, Hoshino K, Sato K, Yoshida A, Hayakawa I, Bures M, et al. Mechanism of differential activities of ofloxacin enantiomers. Antimicrob Agents Chemother. 1996;40:1775-84 pubmed
Sato K, Matsuura Y, Inoue M, Une T, Osada Y, Ogawa H, et al. In vitro and in vivo activity of DL-8280, a new oxazine derivative. Antimicrob Agents Chemother. 1982;22:548-53 pubmed
Seibert G, Limbert M, Klesel N. Comparison of the antibacterial in vitro and in vivo activity of ofloxacin (HOE 280 DL 8280) and nalidixic acid analogues. Eur J Clin Microbiol. 1983;2:548-53 pubmed
Atarashi S, Yokohama S, Yamazaki K, Sakano K, Imamura M, Hayakawa I. Synthesis and antibacterial activities of optically active ofloxacin and its fluoromethyl derivative. Chem Pharm Bull (Tokyo). 1987;35:1896-902 pubmed
Egawa H, Miyamoto T, Matsumoto J. A new synthesis of 7H-pyrido[1,2,3-de][1,4]benzoxazine derivatives including an antibacterial agent, ofloxacin. Chem Pharm Bull (Tokyo). 1986;34:4098-102 pubmed
Monk J, Campoli Richards D. Ofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1987;33:346-91 pubmed

product information

Product ID :

ALX-380-297

Catalog Number :

ALX-380-297-G005

Product Name :

Ofloxacin

Product Type :

Biochemical

Size :

5 g

list of Pubmed id :

17145798, 17035499, 15769740, 10508721, 8843280, 6960805, 6230226, 3664798, 3470155, 3297617

Product Description :

Fluoroquinolone with broad-spectrum antibacterial activity against most Gram-negative and Gram-positive bacteria. Effective against Mycobacterium tuberculosis.

ALTnames :

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazin-6-carboxylic acid, DL 8280

Purity :

≥98% (UHPLC)

Storage :

-20°C