This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Colchicine
catalog :
ALX-380-033-G001
quantity :
1 g
citations: 10
Reference
Grevesse T, Dabiri B, Parker K, Gabriele S. Opposite rheological properties of neuronal microcompartments predict axonal vulnerability in brain injury. Sci Rep. 2015;5:9475 pubmed publisher
Molad Y. Update on colchicine and its mechanism of action. Curr Rheumatol Rep. 2002;4:252-6 pubmed
Feng G, Kaplowitz N. Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody. J Clin Invest. 2000;105:329-39 pubmed
Hu Y, Li S, Shyy J, Chien S. Sustained JNK activation induces endothelial apoptosis: studies with colchicine and shear stress. Am J Physiol. 1999;277:H1593-9 pubmed publisher
Gorman A, Bonfoco E, Zhivotovsky B, Orrenius S, Ceccatelli S. Cytochrome c release and caspase-3 activation during colchicine-induced apoptosis of cerebellar granule cells. Eur J Neurosci. 1999;11:1067-72 pubmed
Engelborghs Y. General features of the recognition by tubulin of colchicine and related compounds. Eur Biophys J. 1998;27:437-45 pubmed
Hamel E. Antimitotic natural products and their interactions with tubulin. Med Res Rev. 1996;16:207-31 pubmed
Lindenboim L, Haviv R, Stein R. Inhibition of drug-induced apoptosis by survival factors in PC12 cells. J Neurochem. 1995;64:1054-63 pubmed
Bonfoco E, Ceccatelli S, Manzo L, Nicotera P. Colchicine induces apoptosis in cerebellar granule cells. Exp Cell Res. 1995;218:189-200 pubmed
Farrell K, Wilson L. Proposed mechanism for colchicine poisoning of microtubules reassembled in vitro from Strongylocentrotus purpuratus sperm tail outer doublet tubulin. Biochemistry. 1980;19:3048-54 pubmed
product information
Product ID :
ALX-380-033
Catalog Number :
ALX-380-033-G001
Product Name :
Colchicine
Product Type :
Biochemical
Size :
1 g
list of Pubmed id :
25820512, 12010611, 10675359, 10516199, 10103099, 9760725, 8656780, 7861134, 7537689, 7397118
Product Description :
Depolymerizes microtubules and inhibits tubulin polymerization. Induces apoptosis in a variety of cells.
Purity :
≥94% (HPLC)
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.