This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Jasplakinolide
catalog :
ALX-350-275-C100
quantity :
100 µg
citations: 10
Reference
Chimura T, Launey T, Yoshida N. Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo. PLoS ONE. 2015;10:e0125119 pubmed publisher
Zhang Y, Zhang L, Li Y, Sun S, Tan H. Different contributions of clathrin- and caveolae-mediated endocytosis of vascular endothelial cadherin to lipopolysaccharide-induced vascular hyperpermeability. PLoS ONE. 2014;9:e106328 pubmed publisher
Lawrence E, Mandato C. Mitochondria localize to the cleavage furrow in mammalian cytokinesis. PLoS ONE. 2013;8:e72886 pubmed publisher
Boulant S, Kural C, Zeeh J, Ubelmann F, Kirchhausen T. Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol. 2011;13:1124-31 pubmed publisher
Yokoyama K, Kaji H, He J, Tanaka C, Hazama R, Kamigaki T, et al. Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes. J Biol Chem. 2011;286:5375-82 pubmed publisher
Flannagan R, Harrison R, Yip C, Jaqaman K, Grinstein S. Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets. J Cell Biol. 2010;191:1205-18 pubmed publisher
Lázaro Diéguez F, Aguado C, Mato E, Sanchez Ruiz Y, Esteban I, Alberch J, et al. Dynamics of an F-actin aggresome generated by the actin-stabilizing toxin jasplakinolide. J Cell Sci. 2008;121:1415-25 pubmed publisher
Visegrady B, Lorinczy D, Hild G, Somogyi B, Nyitrai M. A simple model for the cooperative stabilisation of actin filaments by phalloidin and jasplakinolide. FEBS Lett. 2005;579:6-10 pubmed
Rosado J, Jenner S, Sage S. A role for the actin cytoskeleton in the initiation and maintenance of store-mediated calcium entry in human platelets. Evidence for conformational coupling. J Biol Chem. 2000;275:7527-33 pubmed
Bubb M, Spector I, Beyer B, Fosen K. Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations. J Biol Chem. 2000;275:5163-70 pubmed
product information
Product ID :
ALX-350-275
Catalog Number :
ALX-350-275-C100
Product Name :
Jasplakinolide
Product Type :
Biochemical
Size :
100 µg
list of Pubmed id :
25905636, 25180771, 23991162, 21841790, 21169636, 21135140, 18398002, 15620683, 10713057, 10671562
Product Description :
Cell permeable F-actin probe. Induces actin polymerization. Completely inhibits the binding of phalloidin to F-actin. Antifungal and anti-proliferative agent.
ALTnames :
Jaspamide
Purity :
≥97% (HPLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.