DTT | Enzo Life Sciences ALX-280-001-G050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

DTT

catalog :

ALX-280-001-G050

quantity :

50 g

citations: 6

Reference
Liu Y, Lear T, Zhao Y, Zhao J, Zou C, Chen B, et al. F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7. Cell Death Dis. 2015;6:e1630 pubmed publisher
Qin L, Wang Z, Tao L, Wang Y. ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy. 2010;6:239-47 pubmed
Cleland W. DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS. Biochemistry. 1964;3:480-2 pubmed
Gailis L. Cleland's reagents block lethal and hypnotic effects of pentobarbital. Eur J Pharmacol. 1994;292:39-42 pubmed
Klonne D, Johnson D. Enzyme activity and sulfhydryl status in rat renal cortex following mercuric chloride and dithiothreitol administration. Toxicol Lett. 1988;42:199-205 pubmed
Lauriault V, O Brien P. Molecular mechanism for prevention of N-acetyl-p-benzoquinoneimine cytotoxicity by the permeable thiol drugs diethyldithiocarbamate and dithiothreitol. Mol Pharmacol. 1991;40:125-34 pubmed

product information

Product ID :

ALX-280-001

Catalog Number :

ALX-280-001-G050

Product Name :

DTT

Product Type :

Biochemical

Size :

50 g

list of Pubmed id :

25654763, 20104019, 14192894, 7867688, 2841777, 1649964

Product Description :

Cell permeable protective agent for SH groups, maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. ER-stress inducer.

ALTnames :

1,4-Dithio-DL-threitol, DL-Dithiothreitol, Cleland's Reagent

Purity :

≥98% (Assay by Iodometric Titration)

Storage :

+4°C