This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Fenofibrate
catalog :
ALX-270-481-G005
quantity :
5 g
citations: 6
Reference
Oosterveer M, Grefhorst A, van Dijk T, Havinga R, Staels B, Kuipers F, et al. Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice. J Biol Chem. 2009;284:34036-44 pubmed publisher
Panigrahy D, Kaipainen A, Huang S, Butterfield C, Barnes C, Fannon M, et al. PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition. Proc Natl Acad Sci U S A. 2008;105:985-90 pubmed publisher
Pierno S, Didonna M, Cippone V, De Luca A, Pisoni M, Frigeri A, et al. Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study. Br J Pharmacol. 2006;149:909-19 pubmed
Saidi S, Holland C, Charnock Jones D, Smith S. In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer. Mol Cancer. 2006;5:13 pubmed
Chaput E, Maubrou Sanchez D, Bellamy F, Edgar A. Fenofibrate protects lipoproteins from lipid peroxidation: synergistic interaction with alpha-tocopherol. Lipids. 1999;34:497-502 pubmed
Wulfert E, Boissard G, Legendre C, Baron C. Inhibition of membrane-bound hepatic 3 hydroxy-3 methyl glutaryl CoA reductase as the consequence of altered membrane fluidity. Artery. 1981;9:120-31 pubmed
product information
Product ID :
ALX-270-481
Catalog Number :
ALX-270-481-G005
Product Name :
Fenofibrate
Product Type :
Biochemical
Size :
5 g
list of Pubmed id :
19801551, 18199835, 17031388, 16569247, 10380122, 7295045
Product Description :
Hypolipidemic compound. PPARα (peroxisome proliferator-activated receptor α) agonist (EC50=18µM for mouse and EC50=30µM for human PPARα). Also binds to PPARγ, but with at least 10-fold less affinity and is inactive at PPARδ (up to EC50=100µM).
ALTnames :
2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic acid 1-methylethyl ester, Procetofen
Purity :
≥98% (HPLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.