Salubrinal | Enzo Life Sciences ALX-270-428-M001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Salubrinal

catalog :

ALX-270-428-M001

quantity :

1 mg

citations: 4

Reference
Goldberg A, Draz H, Montes Grajales D, Olivero VerbÃ©l J, Safe S, Sanderson J. 3,3'-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and -independent prostate cancer cells. Genes Cancer. 2015;6:265-280 pubmed
Razi M, Chan E, Tooze S. Early endosomes and endosomal coatomer are required for autophagy. J Cell Biol. 2009;185:305-21 pubmed publisher
Boyce M, Py B, Ryazanov A, Minden J, Long K, Ma D, et al. A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death. Cell Death Differ. 2008;15:589-99 pubmed publisher
Boyce M, Bryant K, Jousse C, Long K, Harding H, Scheuner D, et al. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science. 2005;307:935-9 pubmed

product information

Product ID :

ALX-270-428

Catalog Number :

ALX-270-428-M001

Product Name :

Salubrinal

Product Type :

Biochemical

Size :

1 mg

list of Pubmed id :

26124925, 19364919, 18188169, 15705855

Product Description :

Cell permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Protects ER stress-induced apoptosis (EC50~15µM in PC12 cells stimulated with 750ng/ml of tunicamycin (Prod. No. BML-CC104)).

Purity :

≥98% (HPLC(UV))

Storage :

-20°C