SC-560 | Enzo Life Sciences ALX-270-427-M005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

SC-560

catalog :

ALX-270-427-M005

quantity :

5 mg

citations: 4

Reference
Soontrapa K, Honda T, Sakata D, Yao C, Hirata T, Hori S, et al. Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression. Proc Natl Acad Sci U S A. 2011;108:6668-73 pubmed publisher
Li W, Wang J, Jiang H, Xu X, Zhang J, Liu M, et al. Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian carcinoma in vivo. Int J Mol Sci. 2011;12:668-81 pubmed publisher
Smith C, Zhang Y, Koboldt C, Muhammad J, Zweifel B, Shaffer A, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998;95:13313-8 pubmed
Masferrer J, Zweifel B, Manning P, Hauser S, Leahy K, Smith W, et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci U S A. 1994;91:3228-32 pubmed

product information

Product ID :

ALX-270-427

Catalog Number :

ALX-270-427-M005

Product Name :

SC-560

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

21460251, 21340007, 9789085, 8159730

Product Description :

Selective COX-1 inhibitor (IC50=9nM). Shows 700-fold more selectivity over COX-2 (IC50=6.3µM). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2, and dermal PGE2 production. Orally active in rat.

ALTnames :

5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole

Purity :

≥98%

Storage :

-20°C