Sodium butyrate | Enzo Life Sciences ALX-270-301-G001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Sodium butyrate

catalog :

ALX-270-301-G001

quantity :

1 g

citations: 7

Reference
Huber K, Doyon G, Plaks J, Fyne E, Mellors J, Sluis Cremer N. Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells. J Biol Chem. 2011;286:22211-8 pubmed publisher
Yang J, Kawai Y, Hanson R, Arinze I. Sodium butyrate induces transcription from the G alpha(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway. J Biol Chem. 2001;276:25742-52 pubmed
Nakamura M, Saito H, Ebinuma H, Wakabayashi K, Saito Y, Takagi T, et al. Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor. J Cell Physiol. 2001;187:392-401 pubmed
Demary K, Wong L, Spanjaard R. Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells. Cancer Lett. 2001;163:103-7 pubmed
Bernhard D, Ausserlechner M, Tonko M, Loffler M, Hartmann B, Csordas A, et al. Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts. FASEB J. 1999;13:1991-2001 pubmed
Schwartz B, Lamprecht S, Polak Charcon S, Niv Y, Kim Y. Induction of the differentiated phenotype in human colon cancer cell is associated with the attenuation of subcellular tyrosine phosphorylation. Oncol Res. 1995;7:277-87 pubmed
Candido E, Reeves R, Davie J. Sodium butyrate inhibits histone deacetylation in cultured cells. Cell. 1978;14:105-13 pubmed

product information

Product ID :

ALX-270-301

Catalog Number :

ALX-270-301-G001

Product Name :

Sodium butyrate

Product Type :

Biochemical

Size :

1 g

list of Pubmed id :

21531716, 11337508, 11319763, 11163113, 10544182, 8527862, 667927

Product Description :

Short-chain fatty acid shown to be an inhibitor of histone deacetylases (HDACs). Induces apoptosis. Restores contextual memory in transgenic mouse model of Alzheimer's. Induces pancreatic progenitor formation. Directs differentiation of mouse embryonic stem cells to hepatocytes with Cytokine Activin A. Sodium butyrate interferes with signal transduction processes, as well as, inhibits c-myc splicing.

Purity :

≥95% (HPLC)

Storage :

-20°C