Rosmarinic acid | Enzo Life Sciences ALX-270-253-M010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Rosmarinic acid

catalog :

ALX-270-253-M010

quantity :

10 mg

citations: 10

Reference
Huang S, Zheng R. Rosmarinic acid inhibits angiogenesis and its mechanism of action in vitro. Cancer Lett. 2006;239:271-80 pubmed
Renzulli C, Galvano F, Pierdomenico L, Speroni E, Guerra M. Effects of rosmarinic acid against aflatoxin B1 and ochratoxin-A-induced cell damage in a human hepatoma cell line (Hep G2). J Appl Toxicol. 2004;24:289-96 pubmed
Osakabe N, Yasuda A, Natsume M, Yoshikawa T. Rosmarinic acid inhibits epidermal inflammatory responses: anticarcinogenic effect of Perilla frutescens extract in the murine two-stage skin model. Carcinogenesis. 2004;25:549-57 pubmed
Won J, Hur Y, Hur E, Park S, Kang M, Choi Y, et al. Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner. Eur J Immunol. 2003;33:870-9 pubmed
Kang M, Yun S, Won J. Rosmarinic acid inhibits Ca2+-dependent pathways of T-cell antigen receptor-mediated signaling by inhibiting the PLC-gamma 1 and Itk activity. Blood. 2003;101:3534-42 pubmed
Nakazawa T, Ohsawa K. Metabolism of rosmarinic acid in rats. J Nat Prod. 1998;61:993-6 pubmed
Bult H, Herman A, Rampart M. Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. Br J Pharmacol. 1985;84:317-27 pubmed
Rampart M, Beetens J, Bult H, Herman A, Parnham M, Winkelmann J. Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid. Biochem Pharmacol. 1986;35:1397-400 pubmed
Kimura Y, Okuda H, Okuda T, Hatano T, Arichi S. Studies on the activities of tannins and related compounds, X. Effects of caffeetannins and related compounds on arachidonate metabolism in human polymorphonuclear leukocytes. J Nat Prod. 1987;50:392-9 pubmed
Peake P, Pussell B, Martyn P, Timmermans V, Charlesworth J. The inhibitory effect of rosmarinic acid on complement involves the C5 convertase. Int J Immunopharmacol. 1991;13:853-7 pubmed

product information

Product ID :

ALX-270-253

Catalog Number :

ALX-270-253-M010

Product Name :

Rosmarinic acid

Product Type :

Biochemical

Size :

10 mg

list of Pubmed id :

16239062, 15300717, 14729597, 12672052, 12511421, 9722482, 3838489, 3516156, 2822857, 1761351

Product Description :

Naturally occurring polyphenolic compound with antioxidant and anti-inflammatory properties.Inhibits several complement-dependent inflammatory processes via inhibition of the C5 convertase. Anticarcinogenic. Inhibitor of lipid peroxidation, TCR-induced T cell activation and proliferation.

ALTnames :

(R)-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2E-propenyl]oxy]-3,4-dihydroxy-benzenepropanoic acid

Purity :

≥97% (Assay)

Storage :

Ambient