Aminopurvalanol A | Enzo Life Sciences ALX-270-249-M005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Aminopurvalanol A

catalog :

ALX-270-249-M005

quantity :

5 mg

citations: 3

Reference
Le Breton M, Belle R, Cormier P, Mulner Lorillon O, Morales J. M-phase regulation of the recruitment of mRNAs onto polysomes using the CDK1/cyclin B inhibitor aminopurvalanol. Biochem Biophys Res Commun. 2003;306:880-6 pubmed
Chang Y, Gray N, Rosania G, Sutherlin D, Kwon S, Norman T, et al. Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors. Chem Biol. 1999;6:361-75 pubmed
Rosania G, Merlie J, Gray N, Chang Y, Schultz P, Heald R. A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts. Proc Natl Acad Sci U S A. 1999;96:4797-802 pubmed

product information

Product ID :

ALX-270-249

Catalog Number :

ALX-270-249-M005

Product Name :

Aminopurvalanol A

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

12821124, 10375538, 10220373

Product Description :

Cell permeable, reversible and competitive inhibitor of CDK1/cyclin B (IC50=33nM), CDK2/cyclin A (IC50=33nM), CDK2/cyclin E (IC50=28nM) and CDK5/p35 (IC50=20nM).

ALTnames :

(2R)-2-((6-((3-Amino-5-chlorophenyl)amino)-9-(1-methylethyl)-9H-purin-2-yl)amino)-3-methyl-1-butanol, NG-97

Purity :

≥97% (HPLC)

Storage :

+4°C