N-ω-Propyl-L-arginine | Enzo Life Sciences ALX-270-203-M025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

N-ω-Propyl-L-arginine

catalog :

ALX-270-203-M025

quantity :

25 mg

citations: 8

Reference
Klamer D, ENGEL J, Svensson L. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004;503:103-7 pubmed
Gowda C, Toomayan G, Qi W, Chen L, Cai Y, Allen D, et al. The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle. Nitric Oxide. 2004;11:17-24 pubmed
Fedorov R, Hartmann E, Ghosh D, Schlichting I. Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms. J Biol Chem. 2003;278:45818-25 pubmed
Boer R, Ulrich W, Klein T, Mirau B, Haas S, Baur I. The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes. Mol Pharmacol. 2000;58:1026-34 pubmed
Cooper G, Mialkowski K, Wolff D. Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform. Arch Biochem Biophys. 2000;375:183-94 pubmed
Huang H, Martasek P, Roman L, Masters B, Silverman R. N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. J Med Chem. 1999;42:3147-53 pubmed
Lee Y, Marletta M, Martasek P, Roman L, Masters B, Silverman R. Conformationally-restricted arginine analogues as alternative substrates and inhibitors of nitric oxide synthases. Bioorg Med Chem. 1999;7:1097-104 pubmed
Zhang H, Fast W, Marletta M, Martasek P, Silverman R. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997;40:3869-70 pubmed

product information

Product ID :

ALX-270-203

Catalog Number :

ALX-270-203-M025

Product Name :

N-ω-Propyl-L-arginine

Product Type :

Biochemical

Size :

25 mg

list of Pubmed id :

15496304, 15350553, 12954642, 12954642, 11040050, 10683266, 10447959, 10428379, 9397167

Product Description :

Potent and selective inhibitor of neuronal nitric oxide synthase (nNOS; NOS I) relative to inducible nitric oxide synthase (iNOS; NOS II) (3158-fold) and endothelial nitric oxide synthase (eNOS; NOS III) (149-fold).

ALTnames :

N5-[Imino(propylamino)methyl]-L-ornithine

Purity :

≥98% (TLC)

Storage :

-20°C