Ebselen | Enzo Life Sciences ALX-270-097-M005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Ebselen

catalog :

ALX-270-097-M005

quantity :

5 mg

citations: 10

Reference
Tiegs G, Kusters S, Künstle G, Hentze H, Kiemer A, Wendel A. Ebselen protects mice against T cell-dependent, TNF-mediated apoptotic liver injury. J Pharmacol Exp Ther. 1998;287:1098-104 pubmed
Sies H, Klotz L, Sharov V, Assmann A, Briviba K. Protection against peroxynitrite by selenoproteins. Z Naturforsch C. 1998;53:228-32 pubmed
Spallholz J. Free radical generation by selenium compounds and their prooxidant toxicity. Biomed Environ Sci. 1997;10:260-70 pubmed
Sies H, Masumoto H. Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite. Adv Pharmacol. 1997;38:229-46 pubmed
Nikawa T, Schuch G, Wagner G, Sies H. Interaction of ebselen with glutathione S-transferase and papain in vitro. Biochem Pharmacol. 1994;47:1007-12 pubmed
Schewe C, Schewe T, Wendel A. Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione. Biochem Pharmacol. 1994;48:65-74 pubmed
Noguchi N, Gotoh N, Niki E. Effects of ebselen and probucol on oxidative modifications of lipid and protein of low density lipoprotein induced by free radicals. Biochim Biophys Acta. 1994;1213:176-82 pubmed
Sies H. Ebselen: a glutathione peroxidase mimic. Methods Enzymol. 1994;234:476-82 pubmed
Schewe T. Molecular actions of ebselen--an antiinflammatory antioxidant. Gen Pharmacol. 1995;26:1153-69 pubmed
Sies H. Ebselen. Methods Enzymol. 1995;252:341-2 pubmed

product information

Product ID :

ALX-270-097

Catalog Number :

ALX-270-097-M005

Product Name :

Ebselen

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

9864298, 9618937, 9315319, 8895811, 8147899, 8043032, 8025128, 7808321, 7590103, 7476371

Product Description :

Selenium-based inhibitor of protein kinase C, NADPH, 5-lipoxygenase, cyclooxygenase (COX) and NADPH oxidase. Anti-inflammatory antioxidant. Mimics glutathione peroxidase. Inhibits oxidative modifications of low density lipoproteins (LDL). Protects cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.

Purity :

≥98% (HPLC)

Storage :

-20°C