This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
3-Aminobenzamide
catalog :
ALX-270-044-G005
quantity :
5 g
citations: 10
Reference
Yamasaki M, Mine Y, Nishimura M, Fujita S, Sakakibara Y, Suiko M, et al. Genistein induces apoptotic cell death associated with inhibition of the NF-?B pathway in adult T-cell leukemia cells. Cell Biol Int. 2013;37:742-7 pubmed publisher
Kleine H, Poreba E, Lesniewicz K, Hassa P, Hottiger M, Litchfield D, et al. Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol Cell. 2008;32:57-69 pubmed publisher
Pogrebniak A, Schemainda I, Azzam K, Pelka Fleischer R, Nüssler V, Hasmann M. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents. Eur J Med Res. 2006;11:313-21 pubmed
Kuo M, Chau Y, Wang J, Shiah S. Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells. Biochem Biophys Res Commun. 1996;219:502-8 pubmed
Nosseri C, Coppola S, Ghibelli L. Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis. Exp Cell Res. 1994;212:367-73 pubmed
Malorni W, Rainaldi G, Straface E, Rivabene R, Cossarizza A, Salvioli S, et al. Cell death protection by 3-aminobenzamide: impairment of cytoskeleton function in human NK cell-mediated killing. Biochem Biophys Res Commun. 1994;199:1250-5 pubmed
Monti D, Cossarizza A, Salvioli S, Franceschi C, Rainaldi G, Straface E, et al. Cell death protection by 3-aminobenzamide and other poly(ADP-ribose)polymerase inhibitors: different effects on human natural killer and lymphokine activated killer cell activities. Biochem Biophys Res Commun. 1994;199:525-30 pubmed
Malorni W, Rivabene R, Straface E, Rainaldi G, Monti D, Salvioli S, et al. 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem Biophys Res Commun. 1995;207:715-24 pubmed
Heller B, Wang Z, Wagner E, Radons J, Burkle A, Fehsel K, et al. Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J Biol Chem. 1995;270:11176-80 pubmed
Kozak K, Ross I. Signal transduction in Coprinus congregatus: evidence for the involvement of G proteins in blue light photomorphogenesis. Biochem Biophys Res Commun. 1991;179:1225-31 pubmed
product information
Product ID :
ALX-270-044
Catalog Number :
ALX-270-044-G005
Product Name :
3-Aminobenzamide
Product Type :
Biochemical
Size :
5 g
list of Pubmed id :
23526666, 18851833, 17052966, 8605017, 8187831, 8147867, 8135793, 7864864, 7744749, 1930168
Product Description :
Inhibits endogenous poly-ADP-ribosyltransferases often present in membrane preparations with minimal effect of bacterial toxin mediated ADP-ribosylation. Inhibits nitric oxide-induced apoptosis but not differentiation in HL-60 cells. Protects cells from oxygen radical and nitric oxide toxicity. Inhibits stress-induced apoptosis.
ALTnames :
3-AB
Purity :
≥97% (GC)
Storage :
Ambient
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.