Proteasome inhibitor I (aldehyde) | Enzo Life Sciences ALX-260-089-M001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Proteasome inhibitor I (aldehyde)

catalog :

ALX-260-089-M001

quantity :

1 mg

citations: 4

Reference
Griscavage J, Wilk S, Ignarro L. Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B. Proc Natl Acad Sci U S A. 1996;93:3308-12 pubmed
Traenckner E, Wilk S, Baeuerle P. A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B. EMBO J. 1994;13:5433-41 pubmed
Figueiredo Pereira M, Berg K, Wilk S. A new inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (20S proteasome) induces accumulation of ubiquitin-protein conjugates in a neuronal cell. J Neurochem. 1994;63:1578-81 pubmed
Mori S, Tanaka K, Omura S, Saito Y. Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway. J Biol Chem. 1995;270:29447-52 pubmed

product information

Product ID :

ALX-260-089

Catalog Number :

ALX-260-089-M001

Product Name :

Proteasome inhibitor I (aldehyde)

Product Type :

Peptide

Size :

1 mg

list of Pubmed id :

8622934, 7957109, 7931314, 7493983

Product Description :

Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid (Prod. No. ALX-350-003) through inhibition of IκBα degradation.

ALTnames :

Z-IE(OtBu)AL-CHO, Z-Ile-Glu(OtBu)-Ala-Leu-CHO, PSI

Purity :

≥95% (TLC)

Storage :

-20°C