This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
Furin convertase substrate (fluorogenic)
catalog :
ALX-260-040-M001
quantity :
1 mg
citations: 10
Reference
Cruz L, Biryukov J, Conway M, Meyers C. Cleavage of the HPV16 Minor Capsid Protein L2 during Virion Morphogenesis Ablates the Requirement for Cellular Furin during De Novo Infection. Viruses. 2015;7:5813-30 pubmed publisher
Kang H, Duran C, Abbey C, Kaunas R, Bayless K. Fluid shear stress promotes proprotein convertase-dependent activation of MT1-MMP. Biochem Biophys Res Commun. 2015;460:596-602 pubmed publisher
Cork S, Kaur B, Devi N, Cooper L, Saltz J, Sandberg E, et al. A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40?kDa vasculostatin from tumor suppressor BAI1. Oncogene. 2012;31:5144-52 pubmed publisher
Cain B, Vishnuvardhan D, Wang W, Foulon T, Cadel S, Cohen P, et al. Production, purification, and characterization of recombinant prohormone convertase 5 from baculovirus-infected insect cells. Protein Expr Purif. 2002;24:227-33 pubmed
Kwon B, Han K, Han K, Ju S, Hwang S, Jeon B, et al. Molecular cloning of kpcA gene encoding a Kex2p-like endoprotease from Aspergillus nidulans. Mol Cells. 2001;12:142-7 pubmed
Basak A, Touré B, Lazure C, Mbikay M, Chretien M, Seidah N. Enzymic characterization in vitro of recombinant proprotein convertase PC4. Biochem J. 1999;343 Pt 1:29-37 pubmed
Krysan D, Rockwell N, Fuller R. Quantitative characterization of furin specificity. Energetics of substrate discrimination using an internally consistent set of hexapeptidyl methylcoumarinamides. J Biol Chem. 1999;274:23229-34 pubmed
Munzer J, Basak A, Zhong M, Mamarbachi A, Hamelin J, Savaria D, et al. In vitro characterization of the novel proprotein convertase PC7. J Biol Chem. 1997;272:19672-81 pubmed
Mains R, Berard C, Denault J, Zhou A, Johnson R, Leduc R. PACE4: a subtilisin-like endoprotease with unique properties. Biochem J. 1997;321 ( Pt 3):587-93 pubmed
Azaryan A, Krieger T, Hook V. Purification and characteristics of the candidate prohormone processing proteases PC2 and PC1/3 from bovine adrenal medulla chromaffin granules. J Biol Chem. 1995;270:8201-8 pubmed
product information
Product ID :
ALX-260-040
Catalog Number :
ALX-260-040-M001
Product Name :
Furin convertase substrate (fluorogenic)
Product Type :
Peptide
Size :
1 mg
list of Pubmed id :
26569287, 25800869, 22330140, 11858717, 11561725, 10493908, 10438496, 9242622, 9032441, 7713926
Product Description :
Fluorogenic substrate for furin/SPC1/PACE/PCSK3 and other subtilisin/kexin-like proprotein convertases such as Kex2, SPC2/PC2/PCSK2, SPC3/PCSK1, PACE4/SPC4/PCSK6, SPC5/PC4/PCSK4, SPC6/PC5/PC6/PCSK5, and SPC7/LPC/PC7/PC8/PCSK7. Can be used on live cells. Ex: 360-380 nm, Em: 440-460 nm.
ALTnames :
Boc-RVRR-AMC, Boc-Arg-Val-Arg-Arg-AMC
Purity :
≥95% (HPLC; TLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.