This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
Z-VAD-FMK
catalog :
ALX-260-020-M001
quantity :
1 mg
citations: 17
Reference
Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed publisher
Amiel A, Johnston H, Nedoncelle K, Warner J, Ferreira S, Röttinger E. Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis. Int J Mol Sci. 2015;16:28449-71 pubmed publisher
Yadav N, Kumar S, Kumar R, Srivastava P, Sun L, Rapali P, et al. Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation. Free Radic Biol Med. 2016;90:261-71 pubmed publisher
Uesugi S, Fujisawa N, Yoshida J, Watanabe M, Dan S, Yamori T, et al. Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition. J Antibiot (Tokyo). 2016;69:133-40 pubmed publisher
Mahul Mellier A, Vercruysse F, Maco B, Ait Bouziad N, de Roo M, Muller D, et al. Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death. Cell Death Differ. 2015;22:2107-22 pubmed publisher
Berthou F, Ceppo F, Dumas K, Massa F, Vergoni B, Alemany S, et al. The Tpl2 Kinase Regulates the COX-2/Prostaglandin E2 Axis in Adipocytes in Inflammatory Conditions. Mol Endocrinol. 2015;29:1025-36 pubmed
Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed publisher
Colin D, Hain K, Allan L, Clarke P. Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins. Open Biol. 2015;5:140156 pubmed publisher
Pfister A, Keil M, Kühl M. The Wnt Target Protein Peter Pan Defines a Novel p53-independent Nucleolar Stress-Response Pathway. J Biol Chem. 2015;290:10905-18 pubmed publisher
Liang J, Martinez A, Lane J, Mayor U, Clague M, Urbé S. USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death. EMBO Rep. 2015;16:618-27 pubmed publisher
Moriwaki K, Bertin J, Gough P, Orlowski G, Chan F. Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. Cell Death Dis. 2015;6:e1636 pubmed publisher
Cao Z, Li X, Zou X, Greenwood M, Gerwick W, Murray T. Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons. Mar Drugs. 2015;13:903-19 pubmed publisher
Woolbright B, Dorko K, Antoine D, Clarke J, Gholami P, Li F, et al. Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis. Toxicol Appl Pharmacol. 2015;283:168-77 pubmed publisher
Schilling J, Machkovech H, He L, Diwan A, Schaffer J. TLR4 activation under lipotoxic conditions leads to synergistic macrophage cell death through a TRIF-dependent pathway. J Immunol. 2013;190:1285-96 pubmed publisher
Gangopadhyay N, Luketich J, Opest A, Visus C, Meyer E, Landreneau R, et al. Inhibition of poly(ADP-ribose) polymerase (PARP) induces apoptosis in lung cancer cell lines. Cancer Invest. 2011;29:608-16 pubmed publisher
Fujita M, Yagami T, Fujio M, Tohji C, Takase K, Yamamoto Y, et al. Cytotoxicity of troglitazone through PPAR?-independent pathway and p38 MAPK pathway in renal cell carcinoma. Cancer Lett. 2011;312:219-27 pubmed publisher
Contreras R, Sakagami H, Nakajima H, Shimada J. Type of cell death induced by various metal cations in cultured human gingival fibroblasts. In Vivo. 2010;24:513-7 pubmed
product information
Product ID :
ALX-260-020
Catalog Number :
ALX-260-020-M001
Product Name :
Z-VAD-FMK
Product Type :
Peptide
Size :
1 mg
list of Pubmed id :
26668314, 26633371, 26627937, 26506860, 26138444, 26020725, 25766330, 25761368, 25759387, 25739811
Product Description :
Irreversible, cell permeable broad-spectrum caspase inhibitor.
ALTnames :
Caspase family inhibitor (fluoromethylketone), Z-Val-Ala-DL-Asp-FMK
Purity :
≥98% (HPLC)
Uses :
Can be used as a broad spectrum caspase inhibitor in conjunction with apoptosis detection assays.
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.