MD-2 polyclonal antibody | Enzo Life Sciences ALX-215-063-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

MD-2 polyclonal antibody

catalog :

ALX-215-063-C100

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Product ID :

ALX-215-063

Catalog Number :

ALX-215-063-C100

Product Name :

MD-2 polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

100 µg

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. Toll-like receptor 4 (TLR4), the principal signaling receptor for lipopolysaccharide (LPS) in mammals, requires the binding of MD-2 to its extracellular domain for maximal responsiveness. MD-2 enables TLR4 to respond to a wide variety of LPS partial structures, Gram-negative bacteria, and Gram-positive lipoteichoic acid, but not to Gram-positive bacteria, peptidoglycan, and lipopeptide.

ALTnames :

LY96, Lymphocyte antigen 96, ESOP-1

Immunogen :

Full length recombinant human MD-2.

Buffer :

Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.

Uses :

Detects a band of ~30kDa by Western blot.

Application Summary :

IHC (PS), WB

Storage :

-20°C