HERG1 (CT) (pan) polyclonal antibody | Enzo Life Sciences ALX-215-049-R100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

HERG1 (CT) (pan) polyclonal antibody

catalog :

ALX-215-049-R100

quantity :

100 µl

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

Enzo Life Sciences product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1c	Liu F, Jones D, de Lange W, Robertson G. Cotranslational association of mRNA encoding subunits of heteromeric ion channels. Proc Natl Acad Sci U S A. 2016;113:4859-64 pubmed publisher
	Jones D, Johnson A, Roti Roti E, Liu F, Uelmen R, Ayers R, et al. Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart. J Cell Sci. 2018;131: pubmed publisher
	Jones D, Liu F, Dombrowski N, Joshi S, Robertson G. Dominant negative consequences of a hERG 1b-specific mutation associated with intrauterine fetal death. Prog Biophys Mol Biol. 2016;120:67-76 pubmed publisher

product information

Product ID :

ALX-215-049

Catalog Number :

ALX-215-049-R100

Product Name :

HERG1 (CT) (pan) polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

100 µl

list of Pubmed id :

18559421, 16175187, 16127690, 15800067, 14744775

SPECIES REACTIVITY :

Human, Mouse

Background :

The ether-a-go-go related gene family of K+ channels (HERG/Erg) comprises three members, HERG1/Erg1, HERG2/Erg2, HERG3/Erg3. HERG channel activity is relevant to tumor cell biology. It controls cell proliferation, especially in leukaemias. HERG channels are thus considered novel diagnostic and prognostic factors in human cancers, as well as targets for anti-neoplastic therapies.

ALTnames :

Ether-a-go-go related protein 1 (pan), KCNH2 (pan), Voltage-gated potassium channel subfamily H member 2 (pan), Voltage-gated potassium channel Kv11.1 (pan), Erg1 (pan)

Immunogen :

Recombinant HERG1 (human ether-a-go-go related protein 1) (aa 1106-1158).

Specificity :

Recognizes C-terminal epitope of HERG1 and mouse Erg1. Recognizes both isoforms HERG1A and HERG1B.

Buffer :

Liquid. Neat serum.

Application Summary :

FC, IHC (FS), IHC (PS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage