This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
RIG-I (human) polyclonal antibody (AT111)
catalog :
ALX-210-932-C100
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation
citations: 1
Reference
Kato K, Ahmad S, Zhu Z, Young J, Mu X, Park S, et al. Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol Cell. 2021;81:599-613.e8 pubmed publisher
product information
Product ID :
ALX-210-932
Catalog Number :
ALX-210-932-C100
Product Name :
RIG-I (human) polyclonal antibody (AT111)
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
26609812, 26454171, 18941247
SPECIES REACTIVITY :
Human
Background :
RIG-I (retinoic acid-inducible gene I; Ddx58), a member of the DEAD-box RNA helicases, is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-β (Cardif) in a CARD-CARD-dependent manner resulting in NF-κB and IRF3 activation.
ALTnames :
RIG-1, Retinoic acid-inducible gene 1 protein, DEAD-box protein 58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 M, Probable ATP-dependent RNA helicase DDX58
Immunogen :
Recombinant human RIG-I (aa 201-713).
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Application Summary :
IP, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.