PTX3 polyclonal antibody (biotin conjugate) | Enzo Life Sciences ALX-210-365B-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

PTX3 polyclonal antibody (biotin conjugate)

catalog :

ALX-210-365B-C050

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

biotin

reactivity :

human, mouse, rat, bovine

application :

immunohistochemistry, immunocytochemistry

product information

Product ID :

ALX-210-365B

Catalog Number :

ALX-210-365B-C050

Product Name :

PTX3 polyclonal antibody (biotin conjugate)

Host species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Biotin

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

20920344, 17496115, 15708850, 12538709, 10931803, 9119472, 7949102

SPECIES REACTIVITY :

Human, Mouse, Rat, Chicken

Background :

Pentraxin 3 (PTX3), a member of the pentraxin family, is referred to as a long pentraxin and contains a unique PTX3 domain not found in C-reactive protein (CRP) or (Serum Amyloid P component) SAP. In contrast to CRP, PTX3 is produced from the major cell types involved in atherosclerotic lesions, namely vascular endothelial cells, vascular smooth muscle cells, macrophages, and nutrophils in response to inflammatory stimuli. Moreover, CRP is produced by the liver and represents a systemic response to local inflammation, whereas PTX3 is rapidly produced directly from damaged tissues and directly reflects the inflammatory state of the vasculature. PTX3 levels have been reported to be significantly elevated in acute myocardial infarction, and accordingly, statin treatment significantly decreases PTX3 levels. Due to the fact that PTX3 is able to reflect acute coronary syndrome (ACS) condition better than CRP, it is highly possible that PTX3 is a superior biomarker to predict future cardiovascular events.

ALTnames :

Pentraxin 3, TSG-14, TNF stimulated gene-14

Immunogen :

Recombinant human PTX3.

Specificity :

Recognizes human, mouse and rat PTX3 and chicken homolog PPTX.

Buffer :

Liquid. In PBS containing 0.1% sodium azide.

Uses :

Excellent for use as detection antibody in an ELISA format together with mAb to PTX3 (Prod. No. ALX-804-464 (capture)) and PTX3 standard (Prod. No. ALX-201-124).

Application Summary :

ELISA, ICC, IHC

Storage :

-20°C