This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Early endosomal antigen 1 polyclonal antibody
catalog :
ALX-210-239-C100
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot
citations: 1
Reference
Boal F, Puhar A, Xuereb J, Kunduzova O, Sansonetti P, Payrastre B, et al. PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment. Cell Rep. 2016;14:750-759 pubmed publisher
product information
Product ID :
ALX-210-239
Catalog Number :
ALX-210-239-C100
Product Name :
Early endosomal antigen 1 polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
15121718
SPECIES REACTIVITY :
Mouse
Background :
EEA1 is a 162kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. Zinc-finger-like domains reminiscent of those found in nucleic acid binding proteins are located in the amino and carboxyl-terminal domains of EEA1. The COOH-terminal zinc-finger-like-domain is conserved in several other non-nuclear proteins, some of which are also involved in intracellular protein trafficking. In addition, this domain is an authentic zinc-binding domain and is critical to the intracellular localization of EEA1. Membrane association of EEA1 has been shown to be dependent on phosphatidyl 3-kinase activity, inhibitors of which cause EEA1 to dissociate from early endosomes.
ALTnames :
EEA1
Immunogen :
Synthetic peptide corresponding to aa 1391-1410 (T1391PSSKKPVR. VCDACFNDLQG1410) of human EEA1 (early endosomal antigen 1).
Buffer :
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
Uses :
Detects a band of ~160kDa by Western blot.
Application Summary :
WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.