Myelin basic protein (human brain), (high purity) | Enzo Life Sciences ALX-200-606-M001 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Myelin basic protein (human brain), (high purity)

catalog :

ALX-200-606-M001

quantity :

1 mg

product information

Product ID :

ALX-200-606

Catalog Number :

ALX-200-606-M001

Product Name :

Myelin basic protein (human brain), (high purity)

Product Type :

Protein

Size :

1 mg

Background :

MBP is a peripheral membrane protein, and its interaction with lipids is generally believed to be critical for the formation and stability of the multilamellar myelin sheath. It has been identified as a Ca2+-calmodulin regulated agent for actin polymerization, tropomyosin and actomyosin function, tubulin stabilization, and clathrin assembley. MBP is generally considered to be the antigen responsible for autoimmunity in multiple sclerosis (MS) and it has the capability to induce experimental allergic encephalomyelitis (EAE). MBP is also an endogenous inhibitor of the high-affinity cannabinoid binding site in the brain and a substrate for numerous protein kinases (MAPK, serine/threonine kinase, protein kinase C). MBP is also suggested to be involved in intracellular signalling and as cytoskeletal components.

ALTnames :

MBP

Purity :

≥95% (SDS-PAGE; Immunoblot)

Buffer :

Lyophilized. No preservatives added.

Uses :

Can be used to induce relapsing experimental autoimmune encephalomyelitis in animals. This product may also be used as a substrate for protein kinases. Suitable for use in ELISA or for antigen applications in immunological protocols. Immunoreactivity is verified using polyclonal and monoclonal antibodies against MBP.

Storage :

-20°C