MMP-2/TIMP-2 proenzyme complex (human fibroblasts) | Enzo Life Sciences ALX-200-420-C005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

MMP-2/TIMP-2 proenzyme complex (human fibroblasts)

catalog :

ALX-200-420-C005

quantity :

5 µg

citations: 4

Reference
Kolkenbrock H, Hecker Kia A, Orgel D, Ulbrich N, Will H. Activation of progelatinase A and progelatinase A/TIMP-2 complex by membrane type 2-matrix metalloproteinase. Biol Chem. 1997;378:71-6 pubmed
Kolkenbrock H, Orgel D, Hecker Kia A, Noack W, Ulbrich N. The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor. Eur J Biochem. 1991;198:775-81 pubmed
Knight C, Willenbrock F, Murphy G. A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases. FEBS Lett. 1992;296:263-6 pubmed
Masui Y, Takemoto T, Sakakibara S, Hori H, Nagai Y. Synthetic substrates for vertebrate collagenase. Biochem Med. 1977;17:215-21 pubmed

product information

Product ID :

ALX-200-420

Catalog Number :

ALX-200-420-C005

Product Name :

MMP-2/TIMP-2 proenzyme complex (human fibroblasts)

Product Type :

Protein

Size :

5 µg

list of Pubmed id :

9088534, 1646720, 1537400, 193489

Background :

MMP-2 and TIMP-2 form a stable, but non-covalent 1:1 stoichiometric complex. The complex inhibits active matrix MMP's like collagenases and gelatinases and shows proteolytic activity after activation with APMA (4-aminophenylmercury acetate).

ALTnames :

Matrix metalloproteinase 2/Tissue inhibitor of metalloproteinase 2 Complex

Purity :

≥95% (SDS-PAGE, Western blot)

Buffer :

Liquid. In 50mM TRIS-HCl pH 7.0, 200mM sodium chloride, 5mM CaCl2, 1µM ZnCl2, 0.05% NaN3 and 0.05% BRIJ 35.

Storage :

-80°C