NG-Amino-L-arginine . hydrochloride | Enzo Life Sciences ALX-106-014-M005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

NG-Amino-L-arginine . hydrochloride

catalog :

ALX-106-014-M005

quantity :

5 mg

citations: 10

Reference
Lee A, Noon K, Jianmongkol S, Lau M, Jenkins G, Osawa Y. Metabolism of aminoguanidine, diaminoguanidine, and NG-amino-L-arginine by neuronal NO-synthase and covalent alteration of the heme prosthetic group. Chem Res Toxicol. 2005;18:1927-33 pubmed
Vuletich J, Lowe E, Jianmongkol S, Kamada Y, Kent U, Bender A, et al. Alteration of the heme prosthetic group of neuronal nitric-oxide synthase during inactivation by N(G)-amino-L-arginine in vitro and in vivo. Mol Pharmacol. 2002;62:110-8 pubmed
Bryk R, Lubeskie A, Wolff D. Studies of neuronal nitric oxide synthase inactivation by diverse suicide inhibitors. Arch Biochem Biophys. 1999;369:243-51 pubmed
Wolff D, Lubeskie A. Inactivation of nitric oxide synthase isoforms by diaminoguanidine and NG-amino-L-arginine. Arch Biochem Biophys. 1996;325:227-34 pubmed
Komori Y, Wallace G, Fukuto J. Inhibition of purified nitric oxide synthase from rat cerebellum and macrophage by L-arginine analogs. Arch Biochem Biophys. 1994;315:213-8 pubmed
Gross S, Stuehr D, Aisaka K, Jaffe E, Levi R, Griffith O. Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine. Biochem Biophys Res Commun. 1990;170:96-103 pubmed
Ignarro L, Bush P, Buga G, Wood K, Fukuto J, Rajfer J. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle. Biochem Biophys Res Commun. 1990;170:843-50 pubmed
Fukuto J, Wood K, Byrns R, Ignarro L. NG-amino-L-arginine: a new potent antagonist of L-arginine-mediated endothelium-dependent relaxation. Biochem Biophys Res Commun. 1990;168:458-65 pubmed
Lambert L, Whitten J, Baron B, Cheng H, Doherty N, McDonald I. Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues. Life Sci. 1991;48:69-75 pubmed
Vargas H, Cuevas J, Ignarro L, Chaudhuri G. Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release. J Pharmacol Exp Ther. 1991;257:1208-15 pubmed

product information

Product ID :

ALX-106-014

Catalog Number :

ALX-106-014-M005

Product Name :

NG-Amino-L-arginine . hydrochloride

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

16359183, 12065761, 10486143, 8561501, 7527206, 2372300, 2166511, 2159292, 1846017, 1646327

Product Description :

Potent inhibitor of endothelial and inducible nitric oxide synthase (eNOS/NOS III and iNOS/NOS II).

ALTnames :

L-NAA . HCl

Purity :

≥97% (TLC)(contains traces of L-ornithine and L-arginine)

Storage :

+4°C