NG-Hydroxy-L-arginine . monoacetate | Enzo Life Sciences ALX-106-004-M005 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

NG-Hydroxy-L-arginine . monoacetate

catalog :

ALX-106-004-M005

quantity :

5 mg

citations: 10

Reference
Buga G, Wei L, Bauer P, Fukuto J, Ignarro L. NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms. Am J Physiol. 1998;275:R1256-64 pubmed publisher
Buga G, Singh R, Pervin S, Rogers N, Schmitz D, Jenkinson C, et al. Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production. Am J Physiol. 1996;271:H1988-98 pubmed
Daghigh F, Fukuto J, Ash D. Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: implications for the regulation of nitric oxide biosynthesis by arginase. Biochem Biophys Res Commun. 1994;202:174-80 pubmed
Boucher J, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu J, et al. N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase. Biochem Biophys Res Commun. 1994;203:1614-21 pubmed
Hecker M, Nematollahi H, Hey C, Busse R, Racke K. Inhibition of arginase by NG-hydroxy-L-arginine in alveolar macrophages: implications for the utilization of L-arginine for nitric oxide synthesis. FEBS Lett. 1995;359:251-4 pubmed
Komori Y, Wallace G, Fukuto J. Inhibition of purified nitric oxide synthase from rat cerebellum and macrophage by L-arginine analogs. Arch Biochem Biophys. 1994;315:213-8 pubmed
Schott C, Bogen C, Vetrovsky P, Berton C, Stoclet J. Exogenous NG-hydroxyl-L-arginine causes nitrite production in vascular smooth muscle cells in the absence of nitric oxide synthase activity. FEBS Lett. 1994;341:203-7 pubmed
Marletta M, Yoon P, Iyengar R, Leaf C, Wishnok J. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. Biochemistry. 1988;27:8706-11 pubmed
Wallace G, Fukuto J. Synthesis and bioactivity of N omega-hydroxyarginine: a possible intermediate in the biosynthesis of nitric oxide from arginine. J Med Chem. 1991;34:1746-8 pubmed
Wallace G, Gulati P, Fukuto J. N omega-hydroxy-L-arginine: a novel arginine analog capable of causing vasorelaxation in bovine intrapulmonary artery. Biochem Biophys Res Commun. 1991;176:528-34 pubmed

product information

Product ID :

ALX-106-004

Catalog Number :

ALX-106-004-M005

Product Name :

NG-Hydroxy-L-arginine . monoacetate

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

9756558, 8945918, 8037711, 7945311, 7532597, 7527206, 7511114, 3242600, 2033598, 2018542

Product Description :

Intermediate in the biosynthesis of nitric oxide from L-arginine by nitric oxide synthases (NOS). Inhibitor of arginases.

ALTnames :

L-HOArg . AcOH

Purity :

≥98% (Elemental Analysis)

Storage :

+4°C