product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Dynamin monoclonal antibody (D5)
catalog :
ADI-VAM-SV041-E
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D5
reactivity :
human, mouse, rat, chicken, bovine
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig s2b
Schiffer M, Teng B, Gu C, Shchedrina V, Kasaikina M, Pham V, et al. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 2015;21:601-9 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10,000; fig 1
Fuchs M, Brandst tter J, Regus Leidig H. Evidence for a Clathrin-independent mode of endocytosis at a continuously active sensory synapse. Front Cell Neurosci. 2014;8:60 pubmed publisher
Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
product information
Product ID :
ADI-VAM-SV041
Catalog Number :
ADI-VAM-SV041-E
Product Name :
Dynamin monoclonal antibody (D5)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
Clone :
D5
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Mouse, Rat, Chicken, Bovine
Background :
Dynamin is a 100 kDa GTP binding protein that was first identified as a protein able to bind microtubules. To date, three genes have been found to encode Dynamin isoforms. Dynamin 1 is neuronal specific, Dynamin 2 is ubiquitously expressed and Dynamin 3 localizes to testis, brain and lung. Dynamin may mediate vesicle formation by assembling into a ring structure around the necks of invaginated coated pits that may eventually lead to the closure of the neck and formation of vesicles.
ALTnames :
DNM, DYN
Immunogen :
Recombinant His6-tagged human dynamin.
Buffer :
Liquid. In PBS, pH 7.2, containing 0.1mM PMSF and 50% glycerol.
Uses :
Detects a band of ~100kDa by Western blot.
Application Summary :
FC, IHC, IP, WB
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.