rSec6 monoclonal antibody (9H5) | Enzo Life Sciences ADI-VAM-SV021-D product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

rSec6 monoclonal antibody (9H5)

catalog :

ADI-VAM-SV021-D

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9H5

The same clone is also sold as:

Abcam: ab69740
Invitrogen: MA1-25480
Abnova: MAB16124

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 7

Reference
Dolat L, Spiliotis E. Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion. J Cell Biol. 2016;214:517-27 pubmed publisher
Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
Yu M, Pisitkun T, Wang G, Aranda J, Gonzales P, Tchapyjnikov D, et al. Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct. Am J Physiol Cell Physiol. 2008;295:C661-78 pubmed publisher
Prigent M, Dubois T, Raposo G, Derrien V, Tenza D, Rosse C, et al. ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol. 2003;163:1111-21 pubmed
Kreitzer G, Schmoranzer J, Low S, Li X, Gan Y, Weimbs T, et al. Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells. Nat Cell Biol. 2003;5:126-36 pubmed
Bubeck A, Reusch U, Wagner M, Ruppert T, Muranyi W, Kloetzel P, et al. The glycoprotein gp48 of murine cytomegalovirusL proteasome-dependent cytosolic dislocation and degradation. J Biol Chem. 2002;277:2216-24 pubmed

product information

Product ID :

ADI-VAM-SV021

Catalog Number :

ADI-VAM-SV021-D

Product Name :

rSec6 monoclonal antibody (9H5)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

18596208, 12545172, 11707434

Clone :

9H5

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse, Rat, Sheep, Rabbit, Porcine, Monkey, Hamster, Dog, Chicken, Bovine

Background :

rSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal.

ALTnames :

Exocyst complex component 3

Immunogen :

Recombinant rat Sec6.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~87kDa by Western blot.

Application Summary :

ICC, IHC (PS), WB

Storage :

-20°C