rSec8 monoclonal antibody (14G1) | Enzo Life Sciences ADI-VAM-SV016-D product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

rSec8 monoclonal antibody (14G1)

catalog :

ADI-VAM-SV016-D

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

14G1

reactivity :

human, mouse, rat, dogs, chicken, bovine, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig s9	Pergu R, Dagar S, Kumar H, Kumar R, Bhattacharya J, Mylavarapu S. The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. J Biol Chem. 2019;294:7177-7193 pubmed publisher
western blot; zebrafish ; fig 1d	Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
	Lujan P, Varsano G, Rubio T, Hennrich M, Sachsenheimer T, Gálvez Santisteban M, et al. PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position. J Cell Sci. 2016;129:4130-4142 pubmed
	Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
	Seixas C, Choi S, Polgar N, Umberger N, East M, Zuo X, et al. Arl13b and the exocyst interact synergistically in ciliogenesis. Mol Biol Cell. 2016;27:308-20 pubmed publisher
	He Q, Wang G, Dasgupta S, Dinkins M, Zhu G, Bieberich E. Characterization of an apical ceramide-enriched compartment regulating ciliogenesis. Mol Biol Cell. 2012;23:3156-66 pubmed publisher
	Yu M, Pisitkun T, Wang G, Aranda J, Gonzales P, Tchapyjnikov D, et al. Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct. Am J Physiol Cell Physiol. 2008;295:C661-78 pubmed publisher
	Wang Q, Chen X, Margolis B. PALS1 regulates E-cadherin trafficking in mammalian epithelial cells. Mol Biol Cell. 2007;18:874-85 pubmed
	Polzin A, Shipitsin M, Goi T, Feig L, Turner T. Ral-GTPase influences the regulation of the readily releasable pool of synaptic vesicles. Mol Cell Biol. 2002;22:1714-22 pubmed

product information

Product ID :

ADI-VAM-SV016

Catalog Number :

ADI-VAM-SV016-D

Product Name :

rSec8 monoclonal antibody (14G1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

26582389, 18596208, 17182851, 11865051

Clone :

14G1

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Rat, Sheep, Rabbit, Porcine, Monkey, Hamster, Guinea pig, Fish, Dog, Chicken, Bovine

Background :

rSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal.

ALTnames :

Exocyst complex component 4

Immunogen :

Recombinant rat rSec8.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~110kDa by Western blot.

Application Summary :

ICC, IHC (PS), IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage