VAMP2 monoclonal antibody (SP10) | Enzo Life Sciences ADI-VAM-SV014-E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

VAMP2 monoclonal antibody (SP10)

catalog :

ADI-VAM-SV014-E

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SP10

application :

western blot, immunohistochemistry

citations: 4

Reference
Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
Cho S, Sattar A, Jeong E, Satchi M, Cho J, Dash S, et al. Aquaporin 1 regulates GTP-induced rapid gating of water in secretory vesicles. Proc Natl Acad Sci U S A. 2002;99:4720-4 pubmed
Ferrer Montiel A, Gutierrez L, Apland J, Canaves J, Gil A, Viniegra S, et al. The 26-mer peptide released from SNAP-25 cleavage by botulinum neurotoxin E inhibits vesicle docking. FEBS Lett. 1998;435:84-8 pubmed

product information

Product ID :

ADI-VAM-SV014

Catalog Number :

ADI-VAM-SV014-E

Product Name :

VAMP2 monoclonal antibody (SP10)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

list of Pubmed id :

11917120, 9755864

Clone :

SP10

Isotype :

IgM

SPECIES REACTIVITY :

Human, Mouse, Rat, Xenopus, Porcine, Hamster, Bovine

Background :

Vesicle-associated membrane protein (VAMP), also known as synaptobrevin, is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicles. Two VAMP homologs, VAMP1 and VAMP2, are differentially expressed in the nervous system. VAMP2 is found in neurons associated with autonomic, sensory and integrative functions, and in non-neuronal Langerhans islets and glomerular cells. VAMP is a component of a 20S complex implicated in vesicle docking and fusion, the formation of which involves the interaction of VAMP with syntaxin through an ATP-dependent reaction modulated by synaptotagmin, SNAP-25, alpha-SNAP, and NSF.

ALTnames :

Synaptobrevin, Vesicle-associated membrane protein 2

Immunogen :

Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates using anti-human Synaptophysin monoclonal antibodies.

Buffer :

Liquid. In PBS, pH 7.2, containing 0.1mM PMSF and 50% glycerol.

Uses :

Detects a band of ~18kDa by Western blot.

Application Summary :

IHC, WB

Storage :

-20°C