SNAP-25 monoclonal antibody (SP12) | Enzo Life Sciences ADI-VAM-SV012-F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

SNAP-25 monoclonal antibody (SP12)

catalog :

ADI-VAM-SV012-F

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SP12

application :

western blot

citations: 4

Reference
Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
Jarvis S, Zamponi G. Distinct molecular determinants govern syntaxin 1A-mediated inactivation and G-protein inhibition of N-type calcium channels. J Neurosci. 2001;21:2939-48 pubmed
Honer W, Hu L, Davies P. Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex. Brain Res. 1993;609:9-20 pubmed

product information

Product ID :

ADI-VAM-SV012

Catalog Number :

ADI-VAM-SV012-F

Product Name :

SNAP-25 monoclonal antibody (SP12)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

200 µg

list of Pubmed id :

11312277, 7685234

Clone :

SP12

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

Synaptic vesicle fusion reactions are mediated by a variety of SNAP proteins, including alpha and beta SNAPs and SNAP-25. Together with synaptotagmin and NSF, alpha-SNAP modulates the interaction of SNAP25, VAMP, and syntaxin in an ATP-dependent manner to form a 20S complex associated with synaptic vesicle docking and fusion. beta-SNAP interacts with synaptotagmin and may be involved in calcium-regulated exocytosis.

ALTnames :

Synaptosomal-associated protein 25

Immunogen :

Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates using anti-human Synaptophysin monoclonal antibodies.

Buffer :

Liquid. In PBS, pH 7.2, containing 0.1mM PMSF and 50% glycerol.

Uses :

Detects a band of ~25kDa by Western blot.

Application Summary :

Storage :

-20°C